Griffithsia griffithsin protein

01/01/2022 - "Porcine deltacoronavirus infection is inhibited by Griffithsin in cell culture."
10/01/2020 - "Sustained-release Griffithsin nanoparticle-fiber composites against HIV-1 and HSV-2 infections."
01/01/2020 - "Rapid-Release Griffithsin Fibers for Dual Prevention of HSV-2 and HIV-1 Infections."
04/01/2019 - "In conclusion, Griffithsin was identified as a potent PEDV inhibitor and may represent a candidate drug for preventing PEDV infection."
04/01/2019 - "The results showed that Griffithsin reduced PEDV infection of Vero cells by approximately 82.8%. "

06/01/2013 - "These in vitro findings translated to significant protection against genital herpes in mice treated with 0.1% griffithsin gel. "
06/01/2013 - "Griffithsin protects mice from genital herpes by preventing cell-to-cell spread."

01/01/2020 - "The biologic griffithsin (GRFT) has recently emerged as a candidate to safely prevent sexually transmitted infections (STIs), including human immunodeficiency virus type 1 (HIV-1) and herpes simplex virus 2 (HSV-2). "
10/31/2017 - "Fabrication and Characterization of Griffithsin-modified Fiber Scaffolds for Prevention of Sexually Transmitted Infections."
10/01/2018 - "Development of a Vaginal Fast-Dissolving Insert Combining Griffithsin and Carrageenan for Potential Use Against Sexually Transmitted Infections."
07/01/2016 - "These advances have resulted in renewed interest in developing non-antiretroviral-based microbicides, such as broadly neutralizing antibodies (for example, VRC01) and anti-viral proteins (for example, Griffithsin), as options for persons not wanting to use antiretroviral drugs, and for their potential to prevent multiple sexually transmitted infections."

11/01/2016 - "Griffithsin-Modified Electrospun Fibers as a Delivery Scaffold To Prevent HIV Infection."
08/01/2007 - "Hence, we evaluated griffithsin (GRFT), a 12.7 kDa carbohydrate-binding protein, both native and recombinant GRFT, potently inhibited both CXCR4-and CCR5-tropic HIV infection and transmission in vitro. "
09/04/2012 - "Griffithsin (GRFT) is a lectin that has been shown to inhibit HIV infection by binding to high mannose glycan structures on the surface of gp120, and it is among the most potent HIV entry inhibitors reported so far. "

01/01/2021 - "In this review, we discuss the main lectins that are possible candidates for use in the treatment of Covid-19, highlighting those that have already demonstrated antiviral activity in vivo and in vitro, including mannose-binding lectin, Griffithsin, BanLec, and others. "
01/01/2020 - "RTAM-PAP1 was compared against the SARS-CoV-2 B38 antibody, ricin A chain, a pokeweed antiviral protein from leaves, and the lectin griffithsin using the special CoDockPP COVID-19 version. "