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recombinant human bone morphogenetic protein-2

a member of the TGF-beta superfamily and closely related to the osteogenic/bone morphogenetic proteins
Also Known As:
rhBMP-2 protein, recombinant
Networked: 165 relevant articles (12 outcomes, 31 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Wang, Jeffrey C: 6 articles (05/2019 - 06/2011)
2. Ames, Christopher P: 4 articles (07/2020 - 01/2007)
3. Smith, Justin S: 4 articles (07/2020 - 02/2014)
4. Yoon, S Tim: 4 articles (05/2019 - 08/2011)
5. Bridwell, Keith H: 4 articles (12/2017 - 09/2005)
6. Hsu, Wellington K: 4 articles (03/2016 - 09/2014)
7. Seeherman, Howard J: 4 articles (10/2012 - 08/2008)
8. Lafage, Virginie: 3 articles (07/2020 - 02/2014)
9. Shaffrey, Christopher I: 3 articles (07/2020 - 02/2014)
10. Ye, Shuai: 3 articles (11/2016 - 02/2013)

Related Diseases

1. Pseudarthrosis (Pseudoarthrosis)
2. Osteonecrosis (Kienbock's Disease)
3. Tibial Fractures (Fracture, Tibial)
4. Pain (Aches)
08/01/2016 - "Evaluating the effects of recombinant human bone morphogenetic protein-2 on pain-associated behaviors in a rat model following implantation near the sciatic nerve."
05/01/2019 - "For lumbar arthrodesis, mean Oswestry Disability Index (ODI), visual analogue scale (VAS) pain score, and fusion rates were similar for anterior lumbar interbody fusion (ALIF) using allogenic multipotent adult progenitor cells (Map3) versus recombinant human bone morphogenetic protein-2 (rhBMP-2) in the one comparative lumbar study (90% vs 92%). "
05/01/2019 - "The present study aims to primarily assess differences in orthodontic treatment duration, bone quality around corticotomy sites, postoperative healing, and subjective pain when corticotomy was done conventionally and with the placement of recombinant human bone morphogenetic protein-2 (rhBMP-2). "
05/01/2009 - "The use of dual tapered threaded fusion cages and recombinant human bone morphogenetic protein-2 on an absorbable collagen sponge obtained and maintained intervertebral spinal fusion, improved clinical outcomes, and reduced pain after anterior lumbar interbody arthrodesis in patients with degenerative lumbar disc disease."
09/15/2013 - "To assess clinical outcomes, perioperative complications, revision surgery rates, and recombinant human bone morphogenetic protein-2 (BMP-2)-related osteolysis, heterotopic bone, and unexplained postoperative radiculitis (BMPP) in a group of patients treated with BMP-2-augmented transforaminal lumbar interbody fusion (bTLIF) for the homogeneous diagnosis of discogenic pain syndrome (DPS) and to put forth the algorithm used to make the diagnosis. "
5. Congenital Abnormalities (Deformity)

Related Drugs and Biologics

1. Collagen
2. Teriparatide (Parathar)
3. Heparin (Liquaemin)
4. Intercellular Signaling Peptides and Proteins (Growth Factors)
5. Zoledronic Acid (Zometa)
6. Polylactic Acid-Polyglycolic Acid Copolymer
7. beta-tricalcium phosphate
8. Anti-Bacterial Agents (Antibiotics)
9. Durapatite (Hydroxylapatite)
10. Bone Morphogenetic Proteins (Bone Morphogenetic Protein)

Related Therapies and Procedures

1. Spinal Fusion (Spondylosyndesis)
2. Arthrodesis
3. Off-Label Use
4. Reoperation
5. Microspheres (Microsphere)