icaritin

03/01/2023 - "Moreover, recent studies demonstrate that icaritin can serve as immune-modulating agent to exert anti-tumor effects. "
09/16/2022 - "In our study, CDK2 was found to be a direct target of icaritin in tumor cells. "
05/01/2022 - "In this study, tumor-derived microparticles (MP) were used to establish the PMN model both in vitro and in vivo, and pro-inflammatory mediators were also employed to evaluate the effects of Icaritin (ICT). "
05/01/2022 - "Recent studies claim that Icaritin can regulate the expression of noncoding RNAs (ncRNAs) in cancer development. "
10/12/2018 - "Icaritin is a compound extracted from herb, recent study have found it is able to influence the activity of various types of cancer. "

04/01/2020 - "The aim of the present study was to investigate the protective effects of icaritin on glioblastoma and its underlying mechanisms, with a particular focus on its association with the ER. "
04/01/2020 - "In conclusion, the results of the present study demonstrate that the anti-glioblastoma effects of icaritin may be mediated by its modulation of ERβ."
04/01/2020 - "The results demonstrated that icaritin inhibited the growth of C6 and U87-MG glioblastoma cells in a dose- and time-dependent manner. "
05/01/2019 - "Icaritin inhibits glioblastoma cell viability and glycolysis by blocking the IL-6/Stat3 pathway."
04/01/2018 - "Activation of PPARγ mediates icaritin-induced cell cycle arrest and apoptosis in glioblastoma multiforme."

01/12/2017 - "The current study aimed to investigate icaritin effect and potential mechanism on oral squamous cell carcinoma (OSCC) development. "
01/01/2017 - "The present study is aimed to investigate the apoptosis-inducing effect of icaritin in human oral squamous cell carcinoma (OSCC) cells and the associated mechanisms. "
01/01/2021 - "Icaritin can inhibit cell proliferation and induce apoptosis in Oral Squamous Cell Carcinoma (OSCC). "
01/12/2017 - "Icaritin Reduces Oral Squamous Cell Carcinoma Progression via the Inhibition of STAT3 Signaling."
01/01/2017 - "Icaritin induces mitochondrial apoptosis by up-regulating miR-124 in human oral squamous cell carcinoma cells."

10/03/2023 - "Icaritin (ICT) is a natural compound extracted from anti-osteoporosis herb Epimedium spp. and has been shown to inhibit osteoclast differentiation. "
11/01/2018 - "A bone-targeting delivery system carrying osteogenic phytomolecule icaritin prevents osteoporosis in mice."
10/03/2023 - "Icaritin ameliorates RANKL-mediated osteoclastogenesis and ovariectomy-induced osteoporosis."
01/01/2016 - "Icaritin (ICT), a major component in herb Epimedium brevicornum Maxim., shows beneficial effects for the treatment of osteoporosis and various cancers, and is predominantly metabolized to glucuronidated icaritin (GICT). "
08/01/2015 - "A phytomolecule, icaritin, has been identified and shown to be osteopromotive for the prevention of osteoporosis and osteonecrosis. "

10/01/2017 - "Icaritin (ICT) displays numerous pharmacological activities for the treatment of various cancers, osteoporosis, inflammation, and angiocardiopathy. "
05/01/2013 - "The purpose of this study was to investigate the protective effects of icaritin on inflammation in lipopolysaccharide (LPS) stimulated mouse peritoneal macrophages in vitro and zymosan induced peritonitis model in vivo. "
03/01/2019 - "Icariin and icaritin ameliorated hippocampus neuroinflammation via inhibiting HMGB1-related pro-inflammatory signals in lipopolysaccharide-induced inflammation model in C57BL/6 J mice."