rat Sfrp4 protein

a stromal protein of the secreted Frizzled gene family, during the endometrial cycle and malignancy; RefSeq NM_053544

Also Known As:

Sfrp4 protein, rat; DDC-4 protein, rat; frpAP protein, rat; secreted frizzled related protein-4; secreted frizzled-related protein 4, rat

Networked: 8 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Neoplasm Proteins: 2
    - Oncogene Proteins: 7793
      - Proto-Oncogene Proteins: 7
        rat Sfrp4 protein: 8

Experts

1.	Kumar, Rajiv: 4 articles (03/2007 - 09/2003)
2.	Berndt, Theresa: 2 articles (03/2007 - 09/2003)
3.	Craig, Theodore A: 2 articles (01/2006 - 09/2003)
4.	Schiavi, Susan C: 2 articles (01/2006 - 09/2003)
5.	Vassiliadis, John: 2 articles (01/2006 - 09/2003)
6.	Gultepe, I: 1 article (01/2019)
7.	Konukoglu, D: 1 article (01/2019)
8.	Senyigit, A: 1 article (01/2019)
9.	Uzun, H: 1 article (01/2019)
10.	Basappa,: 1 article (01/2017)

Related Diseases

1.	Oncogenic osteomalacia 08/01/2010 - "Secreted frizzled-related protein-4 (sFRP4) is a member of secreted modulators of Wnt signaling pathways and has been recognized to play important role in the pathogenesis of oncogenic osteomalacia as a potential phosphatonin. " 12/01/2008 - "Expression analysis of fibroblast growth factor-23, matrix extracellular phosphoglycoprotein, secreted frizzled-related protein-4, and fibroblast growth factor-7: identification of fibroblast growth factor-23 and matrix extracellular phosphoglycoprotein as major factors involved in tumor-induced osteomalacia." 03/01/2007 - "Recently, several phosphaturic peptides such as fibroblast growth factor 23 (FGF-23), secreted frizzled-related protein-4 (sFRP-4), extracellular phosphoglycoprotein (MEPE) and fibroblast growth factor 7 (FGF-7) have been shown to play a pathogenic role in several hypophosphatemic disorders such as tumor-induced osteomalacia (TIO), autosomal dominant hypophosphatemic rickets (ADHR), X-linked hypophosphatemic rickets (XLH), the McCune-Albright syndrome (MAS) and fibrous dysplasia (FD). "
2.	Familial Hypophosphatemic Rickets (X-Linked Hypophosphatemia) 03/01/2007 - "Recently, several phosphaturic peptides such as fibroblast growth factor 23 (FGF-23), secreted frizzled-related protein-4 (sFRP-4), extracellular phosphoglycoprotein (MEPE) and fibroblast growth factor 7 (FGF-7) have been shown to play a pathogenic role in several hypophosphatemic disorders such as tumor-induced osteomalacia (TIO), autosomal dominant hypophosphatemic rickets (ADHR), X-linked hypophosphatemic rickets (XLH), the McCune-Albright syndrome (MAS) and fibrous dysplasia (FD). "
3.	Hypophosphatemia 01/01/2006 - "The phosphatonin, secreted frizzled-related protein-4 (sFRP-4), induces phosphaturia and inhibits 25-hydroxyvitamin D 1alpha-hydroxylase activity normally induced in response to hypophosphatemia. "
4.	Neoplasms (Cancer) 09/01/2003 - "We show that secreted frizzled-related protein-4 (sFRP-4), a protein highly expressed in such tumors, is a circulating phosphaturic factor that antagonizes renal Wnt-signaling. "
5.	Chronic Kidney Failure (Chronic Renal Failure) 01/01/2006 - "Phosphate regulation of FGF-23 and secreted frizzled related protein-4 (sFRP-4) was examined in end-stage renal disease patients in the presence and absence of therapeutic phosphate binder usage. "

Related Drugs and Biologics

1.	Fibroblast Growth Factor 7
2.	Fibroblast Growth Factor-23
3.	Islet Amyloid Polypeptide
4.	Glucagon-Like Peptide 1 (GLP 1)
5.	Catenins
6.	Clusterin
7.	Saponins
8.	Proteins (Proteins, Gene)
9.	Phosphates (Orthophosphate)
10.	Peptides (Polypeptides)