Kallikreins

Proteolytic enzymes from the serine endopeptidase family found in normal blood and urine. Specifically, Kallikreins are potent vasodilators and hypotensives and increase vascular permeability and affect smooth muscle. They act as infertility agents in men. Three forms are recognized, PLASMA KALLIKREIN (EC 3.4.21.34), TISSUE KALLIKREIN (EC 3.4.21.35), and PROSTATE-SPECIFIC ANTIGEN (EC 3.4.21.77).

Also Known As:

Kallikrein; Kallidinogenase; Callicrein; Dilminal; Kalliginogenase; Kallikrein A; Kallikrein B'; Kallikrein Light Chain; Kinin-Forming Enzyme; Padutin; alpha-Kallikrein; beta-Kallikrein; beta-Kallikrein B; Enzyme, Kinin-Forming; Kinin Forming Enzyme; Light Chain, Kallikrein; alpha Kallikrein; beta Kallikrein; beta Kallikrein B; Kininogenase

Pharmalogical Action Categories:

Coagulants
Fertility Agents, Male

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Peptide Hydrolases: 23957
      - Serine Proteases: 3726
        Serine Endopeptidases: 11
        Kallikreins: 2114
      - Endopeptidases: 633
        Serine Endopeptidases: 11
        Kallikreins: 2114
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Blood Coagulation Factors: 5376
      - Kallikreins: 2114
Biological Factors: 2472
- Blood Coagulation Factors: 5376
  - Kallikreins: 2114

human KLK12 protein

Bio-Agent Context: Research Results