HOME
PRODUCTS
COMPANY
CONTACT
FAQ
Research
Dictionary
Pharma
Sign Up
FREE
or
Login
Username:
Password:
Remember login
Login
Send password reminder...
R 135853
a sordarin derivative with antifungal activity; structure in first source
Also Known As:
R-135853; R135853
Networked:
1
relevant articles (
1
outcomes,
0
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azepines: 11
R 135853: 1
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Bridged-Ring Compounds: 1
R 135853: 1
Polycyclic Compounds: 6
Bridged-Ring Compounds: 1
R 135853: 1
Experts
1.
Fukuoka, Takashi
: 1 article (01/2005)
2.
Kakuta, Masayo
: 1 article (01/2005)
3.
Kamai, Yasuki
: 1 article (01/2005)
4.
Kuwahara, Shogo
: 1 article (01/2005)
5.
Shibayama, Takahiro
: 1 article (01/2005)
Related Diseases
1.
Candidiasis (Moniliasis)
01/01/2005 - "
albicans, with MICs ranging from 0.03 to 0.06 mug/ml. However, R-135853 exhibited weak or no activity against Candida parapsilosis, Candida krusei, and Aspergillus spp. R-135853 exhibited dose-dependent efficacy against experimental murine hematogenous candidiasis induced by C.
"
01/01/2005 - "
Subcutaneous administration of R-135853 exhibited dose-dependent efficacy against experimental murine esophageal candidiasis induced by fluconazole-resistant C.
"
01/01/2005 - "
Antifungal activities of R-135853, a sordarin derivative, in experimental candidiasis in mice.
"
01/01/2005 - "
These results suggest that R-135853 is promising for the treatment of disseminated or mucosal candidiasis, including fluconazole-refractory infections.
"
2.
Infections
01/01/2005 - "
These results suggest that R-135853 is promising for the treatment of disseminated or mucosal candidiasis, including fluconazole-refractory infections.
"
Related Drugs and Biologics
1.
Fluconazole (Zonal)
2.
sordarin