Type 1 Fibroblast Growth Factor Receptor

A fibroblast growth factor receptor with specificity for FIBROBLAST GROWTH FACTORS; HEPARAN SULFATE PROTEOGLYCAN; and NEURONAL CELL ADHESION MOLECULES. Several variants of the receptor exist due to multiple ALTERNATIVE SPLICING of its mRNA. Fibroblast growth factor receptor 1 contains three extracellular IMMUNOGLOBULIN C2-SET DOMAINS and is a tyrosine kinase that transmits signals through the MAP KINASE SIGNALING SYSTEM.

Also Known As:

Fibroblast Growth Factor Receptor 1; Receptor, Fibroblast Growth Factor, Type 1; CD331 Antigen; FGFR1 Protein; FGFR1 Tyrosine Kinase; Fibroblast Growth Factor Soluble Receptor 1; fms-Like Tyrosine Kinase-2; Antigen, CD331; fms Like Tyrosine Kinase 2

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Phosphotransferases: 42769
      - Phosphotransferases (Alcohol Group Acceptor)
        Protein Kinases: 9677
        Protein-Tyrosine Kinases: 7697
        Receptor Protein-Tyrosine Kinases: 5999
        Type 1 Fibroblast Growth Factor Receptor: 436
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Cell Surface Receptors: 2125
      - Receptor Protein-Tyrosine Kinases: 5999
        Type 1 Fibroblast Growth Factor Receptor: 436
      - Peptide Receptors: 1159
        Growth Factor Receptors: 2663
        Fibroblast Growth Factor Receptors: 1599
        Type 1 Fibroblast Growth Factor Receptor: 436
  - Intracellular Signaling Peptides and Proteins: 32
    - Protein-Tyrosine Kinases: 7697
      - Receptor Protein-Tyrosine Kinases: 5999
        Type 1 Fibroblast Growth Factor Receptor: 436

mouse Fgfr1 protein

Bio-Agent Context: Research Results