Cyclin-Dependent Kinase 2

A key regulator of CELL CYCLE progression. It partners with CYCLIN E to regulate entry into S PHASE and also interacts with CYCLIN A to phosphorylate RETINOBLASTOMA PROTEIN. Its activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P27 and CYCLIN-DEPENDENT KINASE INHIBITOR P21.

Also Known As:

CDK2 Protein; Cdc2-Related Protein Kinase; p33cdk2 Kinase; Cdc2 Related Protein Kinase; Cyclin Dependent Kinase 2; Cdk2 Protein Kinase

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Phosphotransferases: 42769
      - Phosphotransferases (Alcohol Group Acceptor)
        Protein Kinases: 9677
        Protein Serine-Threonine Kinases: 3588
        Proline-Directed Protein Kinases: 28
        Cyclin-Dependent Kinases: 4005
        Cyclin-Dependent Kinase 2: 343
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Cell Cycle Proteins: 807
    - Cyclin-Dependent Kinases: 4005
      - Cyclin-Dependent Kinase 2: 343
  - Intracellular Signaling Peptides and Proteins: 32
    - Protein Serine-Threonine Kinases: 3588
      - Proline-Directed Protein Kinases: 28
        Cyclin-Dependent Kinases: 4005
        Cyclin-Dependent Kinase 2: 343

human CDK2 protein

Bio-Agent Context: Research Results