captodiamine

Captodiamine represents an interesting strategy for achieving benzodiazepine substitution with a low risk of dependence or impairment of cognitive function

Also Known As:

2-((p-(Butylthio)-alpha-phenylbenzyl)thio)-N,N-dimethylethylamine

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Ethylamines: 5
    - captodiamine: 2
- Sulfur Compounds: 278
  - Sulfides: 1062
    - captodiamine: 2
Inorganic Chemicals: 9
- Electrolytes: 16106
  - Ions: 7857
    - Anions: 3501
      - Sulfides: 1062
        captodiamine: 2
- Sulfur Compounds: 278
  - Hydrogen Sulfide: 2764
    - Sulfides: 1062
      - captodiamine: 2

Experts

1.	Regan, Ciaran M: 1 article (10/2013)
2.	Ring, Rebecca M: 1 article (10/2013)
3.	Chabannes, J P: 1 article (09/2004)
4.	Mercier-Guyon, C: 1 article (09/2004)
5.	Saviuc, P: 1 article (09/2004)

Related Diseases

1.	Substance Withdrawal Syndrome (Withdrawal Symptoms) 09/01/2004 - "Analysis of the primary study criterion revealed a statistically significant difference (p < 0.0001) in the emergence of withdrawal symptoms between the two groups in favour of captodiamine at two, six and eight weeks following initiation of therapy. "
2.	Anhedonia 10/01/2013 - "These unique features of captodiamine may contribute to its ability to ameliorate stress-induced anhedonia as the hypothalamus plays a prominent role in regulating HPA axis activity. " 10/01/2013 - "Captodiamine has also been found to ameliorate stress-induced anhedonia, reduce the associated elevations of hypothalamic corticotrophin-releasing factor (CRF) and restore the reductions in hypothalamic BDNF expression. "

Related Drugs and Biologics

1.	Brain-Derived Neurotrophic Factor (BDNF)
2.	Adrenocorticotropic Hormone (ACTH)

Related Therapies and Procedures

1.	Therapeutics