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neuropeptide B

ligand for the orphan receptors GPR7 and GPR8

Networked: 11 relevant articles (0 outcomes, 4 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Nerve Tissue Proteins: 2
    - Neuropeptides: 6772
      - neuropeptide B: 11
- Peptides: 82426
  - Neuropeptides: 6772
    - neuropeptide B: 11

Experts

1.	Czyzewska, Krystyna: 3 articles (01/2021 - 01/2018)
2.	Grzelak, Teresa: 3 articles (01/2021 - 01/2018)
3.	Dmitrzak-Weglarz, Monika: 2 articles (01/2021 - 01/2018)
4.	Dutkiewicz, Agata: 2 articles (01/2021 - 01/2018)
5.	Mikulska, Aniceta Ada: 2 articles (01/2021 - 01/2018)
6.	Paszynska, Elzbieta: 2 articles (01/2021 - 01/2018)
7.	Slopien, Agnieszka: 2 articles (01/2021 - 01/2018)
8.	Tyszkiewicz-Nwafor, Marta: 2 articles (01/2021 - 01/2018)
9.	Decker, Ann M: 1 article (03/2022)
10.	Gamage, Thomas F: 1 article (03/2022)

Related Diseases

1.	Anorexia Nervosa 01/01/2018 - "Neuropeptide B and Vaspin as New Biomarkers in Anorexia Nervosa." 01/01/2021 - "Vaspin (but not neuropeptide B or neuropeptide W) as a possible predictor of body weight normalization in anorexia nervosa." 01/01/2021 - "The aim of the study was to evaluate the correlation between the nutritional status of patients with anorexia nervosa (AN) and levels of vaspin (VASP), neuropeptide B (NPB), neuropeptide W (NPW) and total antioxidant status (TAS). " 01/01/2018 - "The aim of the study was to assess the correlation between the levels of neuropeptide B (NPB), neuropeptide W (NPW), vaspin (VAS), and the total antioxidant status (TAS) in the blood, as well as nutritional status of patients with anorexia nervosa (AN). "
2.	Hyperalgesia 07/12/2005 - "Neuropeptide B-deficient mice demonstrate hyperalgesia in response to inflammatory pain." 01/01/2006 - "In the present study, the effects of intrathecal and i.c.v. application of neuropeptide W-23 and neuropeptide B on the level of mechanical allodynia induced by partial sciatic nerve ligation were tested in rats. " 01/01/2006 - "Intrathecal injection of either neuropeptide W-23 or neuropeptide B attenuated the level of mechanical allodynia in a dose dependent manner at a dose between 0.1 and 10 microg, but i.c.v. injection of either neuropeptide W-23 or neuropeptide B had no effect on the level of mechanical allodynia at a dose between 3 and 30 microg. " 01/01/2006 - "Effects of intrathecal and i.c.v. administration of neuropeptide W-23 and neuropeptide B on the mechanical allodynia induced by partial sciatic nerve ligation in rats."
3.	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 05/01/2019 - "Neuropeptide B and neuropeptide W as new serum predictors of nutritional status and of clinical outcomes in pediatric patients with type 1 diabetes mellitus treated with the use of pens or insulin pumps." 05/01/2019 - "The aim of our study was to determine the relationship between neuropeptide B (NPB), neuropeptide W (NPW), nutritional and antioxidant status and selected fat- and bone-derived factors in type 1 diabetes mellitus (T1DM) treated using pens (T1DM pen group) or insulin pumps (T1DM pump group) in order to investigate the potential role of NPB and NPW in the clinical outcomes of T1DM. "
4.	Pain (Aches) 07/12/2005 - "Neuropeptide B-deficient mice demonstrate hyperalgesia in response to inflammatory pain." 05/31/2005 - "Anti-hyperalgesic effects of intrathecally administered neuropeptide W-23, and neuropeptide B, in tests of inflammatory pain in rats." 03/05/2022 - "Neuropeptides B and W (NPB and NPW) are endogenous ligands of the Neuropeptide B/W Receptor 1 (NPBWR1) which has been implicated in a wide range of functions including regulation of pain and energy homeostasis. "
5.	Body Weight (Weight, Body) 01/01/2021 - "Vaspin (but not neuropeptide B or neuropeptide W) as a possible predictor of body weight normalization in anorexia nervosa." 06/01/2006 - "In this overview, an introduction to the GPCRs and the field of central regulation of food intake is provided together with brief mentioning of some other GPCRs that are also implicated in regulation of body weight, such as the melanin-concentrating hormone (MCH), neuromedin U, prolactin-releasing peptide (PrRP), bombesin, cholecystokinin (CCK), Glucagon-like peptide-1 (GLP-1) (and oxyntomodulin), neuropeptide B (NPB) and neuropeptide W (NPW), opioids peptides, free fatty acid (FFA) receptors (GPR40, GPR41). "

Related Drugs and Biologics

1.	Neuropeptides
2.	4-nitrophenethyl bromide (NPB)
3.	Antioxidants
4.	Insulin (Novolin)
5.	Opioid Analgesics (Opioids)
6.	melanin-concentrating hormone (melanin concentrating hormone)
7.	Prolactin-Releasing Hormone (Prolactin Releasing Hormone)
8.	Ghrelin
9.	Oxyntomodulin
10.	Glucagon-Like Peptide 1 (GLP 1)

Related Therapies and Procedures

1.	Ligation
2.	Therapeutics
3.	Spinal Injections
4.	Analgesia