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14,15-eicosa-5-enoic acid

an eicosatrienoic acid antagonist

Also Known As:

14,15-EEZE; 14,15-eicosa-5(Z)-enoic acid

Networked: 5 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Lipids: 114793
- Fatty Acids: 27405
  - Unsaturated Fatty Acids: 8236
    - Eicosanoids: 3262
      - 8,11,14-Eicosatrienoic Acid: 104
        14,15-eicosa-5-enoic acid: 5

Experts

1.	Hammock, Bruce D: 2 articles (01/2017 - 12/2008)
2.	Ding, Shumei: 1 article (01/2022)
3.	Jiang, Chengyan: 1 article (01/2022)
4.	Jiang, Qingsong: 1 article (01/2022)
5.	Qiu, Hongmei: 1 article (01/2022)
6.	Wu, Ke: 1 article (01/2022)
7.	Yang, Chuang: 1 article (01/2022)
8.	Yang, Junxia: 1 article (01/2022)
9.	Zhang, Jie: 1 article (01/2022)
10.	Chen, Yanying: 1 article (01/2021)

Related Diseases

1.	Hypertrophy 01/01/2022 - "Supplementation with 14,15-EET improved the cardiomyocyte hypertrophy and up-regulated PPARs expression, which were nullified by 14,15-EEZE, a 14,15-EET antagonist. "
2.	Hypoxia (Hypoxemia) 01/01/2017 - "14,15-EEZE (an EET antagonist) attenuated the hypoxia-induced greater elevation of RVSP in sEH-deficient mice, suggesting an EET-mediated increment. " 12/01/2008 - "Both 11,12-EET and hypoxia elicited the membrane translocation of a transient receptor potential (TRP) C6-V5 fusion protein, the latter effect was sensitive to 14,15-EEZE. "
3.	Myocardial Infarction 01/01/2021 - "Methods/Results: We used SRF small interfering RNA (siSRF), SRF small hairpin (shSRF) RNA sequence adenovirus, PI3K/Akt/GSK3β pathway inhibitors, t-AUCB, and 14,15-EEZE (a preparation of EETs antagonists) to treat mouse cardiomyocytes overexpressing miR-1 and mice with myocardial infarction (MI). "
4.	Infarction (Infarctions) 07/01/2008 - "However, 14,15-EEZE did not alter infarct size in sEHKO mice. "

Related Drugs and Biologics

1.	14,15-epoxy-5,8,11-eicosatrienoic acid
2.	Small Interfering RNA (siRNA)
3.	Proteins (Proteins, Gene)
4.	4- (4- (3- adamantan- 1- ylureido)cyclohexyloxy)benzoic acid
5.	11,12-epoxy-5,8,14-eicosatrienoic acid