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surinabant

structure in first source

Also Known As:

5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-ethyl-N-(1-piperidinyl)-1H-pyrazole-3-carboxamide; SR 147778; SR-147778; SR147778

Networked: 6 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrazoles: 61
      - surinabant: 6
  - Piperidines: 17
    - surinabant: 6

Experts

1.	Aubin, Henri-Jean: 1 article (07/2012)
2.	Tonstad, Serena: 1 article (07/2012)
3.	Bermudez-Silva, F J: 1 article (09/2008)
4.	McPartland, J M: 1 article (09/2008)
5.	Viveros, M P: 1 article (09/2008)
6.	de Fonseca, F Rodriguez: 1 article (09/2008)
7.	Bermudez-Silva, Francisco Javier: 1 article (01/2008)
8.	Gallego, Araceli: 1 article (01/2008)
9.	Lamota, Laura: 1 article (01/2008)
10.	Llorente, Ricardo: 1 article (01/2008)

Related Diseases

1.	Alcoholism (Alcohol Abuse) 01/01/2022 - "In this review we summarize and compare Baclofen, Gabapentin, Topiramate, Ondansetron, Varenicline, Aripiprazole, Quetiapine, Clozapine, Antidepressants, Lithium, Neuropeptide Y, Neuropeptide S, Corticotropin-releasing factor antagonists, Oxytocin, PF-05190457, Memantine, Ifenprodil, Samidorphan, Ondelopran, ABT-436, SSR149415, Mifepristone, Ibudilast, Citicoline, Rimonabant, Surinabant, AM4113 and Gamma-hydroxybutyrate While some have shown promising results in the treatment of alcohol use disorder, others have disappointed and should be excluded from further investigation. "
2.	Body Weight (Weight, Body) 07/01/2012 - "The gain in body weight from baseline was reduced with surinabant 2.5 mg/day, 5 mg/day and 10 mg/day (0.75 kg [SE, 0.13], 0.53 kg [SE, 0.13], and 0.24 kg [SE, 0.13], respectively, versus 1.19 kg [SE, 0.13] for placebo; p for trend, < 0.001). " 01/01/2008 - "Adolescence (postnatal days 37-44) and/or post-adolescence (postnatal days 45-59) administration of Surinabant reduced body weight gain, as well as plasma glucose levels and triglycerides. "
3.	Binge Drinking 01/01/2005 - "In Experiment 5, the combination of 3 mg/kg of SR147778 (i.p.) and 0.5 g/kg of alcohol (i.p.), a dose comparable with those usually consumed by sP rats in each drinking binge, failed to induce any conditioned taste aversion. "
4.	Weight Gain 07/01/2012 - "Surinabant did not improve smoking cessation rates compared with placebo, but had a small effect on reducing post-cessation weight gain."
5.	Obesity 09/01/2008 - "Several CB(1) inverse agonists have been developed for the treatment of obesity, including rimonabant, taranabant, and surinabant. "

Related Drugs and Biologics

1.	Rimonabant
2.	Ondansetron (Zofran)
3.	Mifepristone (RU 486)
4.	Sodium Oxybate (gamma Hydroxybutyrate)
5.	Oxytocin (Pitocin)
6.	Neuropeptides
7.	Neuropeptide Y
8.	Memantine (Namenda)
9.	Lithium
10.	Cytidine Diphosphate Choline (Citicoline)

Related Therapies and Procedures

1.	Analgesia