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NSC281612

antineoplastic; structure in first source

Also Known As:

4-(bis(2-((methylsulfonyl)oxy)ethyl)amino)-2-methylbenzaldehyde; DMS612; NSC 281612; NSC-281612

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Aldehydes: 2153
  - Benzaldehydes: 9
    - NSC281612: 3

Experts

1.	Beumer, Jan H: 3 articles (02/2015 - 01/2013)
2.	Parise, Robert A: 3 articles (02/2015 - 01/2013)
3.	Eiseman, Julie L: 2 articles (12/2013 - 01/2013)
4.	Appleman, Leonard J: 1 article (02/2015)
5.	Balasubramaniam, Sanjeeve: 1 article (02/2015)
6.	Bates, Susan E: 1 article (02/2015)
7.	Belani, Chandra P: 1 article (02/2015)
8.	Bonner, William M: 1 article (02/2015)
9.	Bryla, Christine: 1 article (02/2015)
10.	Chu, Edward: 1 article (02/2015)

Related Diseases

1.

Renal Cell Carcinoma (Grawitz Tumor)

02/15/2015 - "DMS612 is a dimethane sulfonate analog with bifunctional alkylating activity and preferential cytotoxicity to human renal cell carcinoma (RCC) in the NCI-60 cell panel. "
01/01/2013 - "Formation of active products of benzaldehyde dimethane sulfonate (NSC 281612, DMS612) in human blood and plasma and their activity against renal cell carcinoma lines."
12/01/2013 - "Benzaldehyde dimethane sulfonate (DMS612, NSC281612, BEN) is an alkylator with activity against renal cell carcinoma, currently in phase I trials. "
01/01/2013 - "Benzaldehyde dimethane sulfonate (BEN, DMS612, NSC281612) is an alkylating agent with activity against renal cell carcinoma and is being evaluated clinically. "

Related Drugs and Biologics

1.	NSC281612
2.	Alkylating Agents
3.	benzaldehyde