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SUN C8079

NF-kappaB inhibitor; structure in first source

Also Known As:

N-(3-(4-(5,6-dimethoxy-3-methyl-1,4-benzoquinon-2-yl)phenyl)propionyl)piperidine

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperidines: 17
    - SUN C8079: 1

Experts

1.	Hara, Masatake: 1 article (03/2004)
2.	Hwang, Myung-Woo: 1 article (03/2004)
3.	Kitaura-Inenaga, Katsura: 1 article (03/2004)
4.	Matsumori, Akira: 1 article (03/2004)
5.	Miyamoto, Tadashi: 1 article (03/2004)
6.	Nishio, Ryosuke: 1 article (03/2004)
7.	Nunokawa, Youichi: 1 article (03/2004)
8.	Ono, Koh: 1 article (03/2004)
9.	Yamaki, Akira: 1 article (03/2004)
10.	Yamamoto, Kanjo: 1 article (03/2004)

Related Diseases

1.	Endotoxemia 03/01/2004 - "We also studied effects of SUN C8079 on lethal endotoxemia and viral myocarditis in mice. " 03/01/2004 - "These findings suggest that the activation of NF-kappaB plays an important role in the pathogenesis of endotoxemia and viral myocarditis, and that the NF-kappaB inhibitor, SUN C8079, may be therapeutic in these disorders." 03/01/2004 - "In addition to protecting mice against lethal endotoxemia, SUN C8079 prevented the development of myocarditis due to the encephalomyocarditis virus (EMCV), and inhibited the expressions of proinflammatory cytokines and the iNOS gene in cardiac tissues. "
2.	Myocarditis (Carditis) 03/01/2004 - "We also studied effects of SUN C8079 on lethal endotoxemia and viral myocarditis in mice. " 03/01/2004 - "These findings suggest that the activation of NF-kappaB plays an important role in the pathogenesis of endotoxemia and viral myocarditis, and that the NF-kappaB inhibitor, SUN C8079, may be therapeutic in these disorders." 03/01/2004 - "In addition to protecting mice against lethal endotoxemia, SUN C8079 prevented the development of myocarditis due to the encephalomyocarditis virus (EMCV), and inhibited the expressions of proinflammatory cytokines and the iNOS gene in cardiac tissues. "

Related Drugs and Biologics

1.	NF-kappa B (NF-kB)
2.	Cytokines