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FR171456

cholesterol synthesis inhibitor produced by Sporormiella minima; structure in first source

Also Known As:

FR 171456

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Cholestanes
      - Sterols: 2245
        Cholesterol: 67133
        FR171456: 3
      - Cholestenes
        Cholesterol: 67133
        FR171456: 3
Lipids: 114793
- Membrane Lipids: 1591
  - Sterols: 2245
    - Cholesterol: 67133
      - FR171456: 3

Experts

1.	Fujii, Takashi: 2 articles (04/2004 - 04/2004)
2.	Hatori, Hidetaka: 2 articles (04/2004 - 04/2004)
3.	Hino, Motohiro: 2 articles (04/2004 - 04/2004)
4.	Shibata, Toshihiro: 2 articles (04/2004 - 04/2004)
5.	Ueda, Hirotsugu: 2 articles (04/2004 - 04/2004)
6.	Aust, Thomas: 1 article (10/2015)
7.	Bergdoll, Marc: 1 article (10/2015)
8.	Filipuzzi, Ireos: 1 article (10/2015)
9.	Fioretto, Celine: 1 article (10/2015)
10.	Frederiksen, Mathias: 1 article (10/2015)

Related Diseases

1.	Hepatocellular Carcinoma (Hepatoma) 04/01/2004 - "FR171456 and FR173945 strongly inhibited cholesterol synthesis in human hepatoma cell line Hep G2. " 04/01/2004 - "FR171456 strongly inhibited the cholesterol synthesis and up-regulated the LDL-receptor expression in human hepatoma cell line Hep G2. "
2.	Hepatitis C 10/12/2015 - "Finally, we show that FR171456 inhibits an artificial Hepatitis C viral replicon, and has broad antifungal activity, suggesting potential additional utility as an anti-infective. "

Related Drugs and Biologics

1.	Cholesterol
2.	LDL Receptors (LDL Receptor)