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notoginsenoside R2

from the roots of commercial ginseng

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Triterpenes: 2493
      - Ginsenosides: 1010
        notoginsenoside R2: 3
Carbohydrates: 22023
- Glycosides: 2119
  - Saponins: 2867
    - Ginsenosides: 1010
      - notoginsenoside R2: 3

Experts

1.	Chen, Wei: 1 article (12/2021)
2.	He, Qianchao: 1 article (12/2021)
3.	Hu, Yueqiang: 1 article (12/2021)
4.	Jiang, Lingfei: 1 article (12/2021)
5.	Liang, Ni: 1 article (12/2021)
6.	Lin, Jiang: 1 article (12/2021)
7.	Qin, Hongling: 1 article (12/2021)
8.	Tao, Ping: 1 article (12/2021)
9.	Wang, Shiying: 1 article (12/2021)
10.	Wu, Lin: 1 article (12/2021)

Related Diseases

1.	Neoplasms (Cancer) 10/04/2023 - "In this study, we investigated the biotransformation of notoginsenoside R1 to 20(S/R)-notoginsenoside R2 using Lactiplantibacillus plantarum S165, compared the inhibitory effects on cancer cell proliferation and conducted a mechanistic study. "
2.	Wounds and Injuries (Trauma) 12/01/2021 - "Notoginsenoside R2 induces colonic microvascular injuries via regulating the Rap1GAP/PI3K/Akt signaling pathway."
3.	Inflammation (Inflammations) 12/01/2021 - "Results: Notoginsenoside R2 alleviated Aβ25-35-triggered neuronal apoptosis and inflammation. " 12/01/2021 - "Notoginsenoside R2 ameliorated AD symptoms by reducing neuronal apoptosis and inflammation, thus suggesting a novel direction for AD pharmacotherapy." 12/01/2021 - "Notoginsenoside R2 reduces Aβ25-35-induced neuronal apoptosis and inflammation via miR-27a/SOX8/β-catenin axis."
4.	Hepatocellular Carcinoma (Hepatoma) 10/04/2023 - "The apoptosis of H22 hepatoma cells was promoted by 20(S/R)-notoginsenoside R2 through the blockade of the PI3K/AKT/mTOR signaling pathway. " 10/04/2023 - "Our results showed that 20(S/R)-notoginsenoside R2 inhibited H22 hepatoma cells proliferation and promoted apoptosis. " 10/04/2023 - "The inhibition effects of 20(S/R)-notoginsenoside R2 on H22 hepatoma cells were assessed by CCK-8 and TUNEL assays, and the underlying mechanism was investigated by Western blotting. " 10/04/2023 - "Enhancing the inhibition of cell proliferation and induction of apoptosis in H22 hepatoma cells through biotransformation of notoginsenoside R1 by Lactiplantibacillus plantarum S165 into 20(S/R)-notoginsenoside R2."

Related Drugs and Biologics

1.	notoginsenoside R1
2.	Catenins
3.	Sincalide

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)