Podophyllotoxin FDA Link Generic

A lignan (LIGNANS) found in PODOPHYLLIN resin from the roots of PODOPHYLLUM plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives.

Also Known As:

Condylox; Wartec; Epipodophyllotoxin; CPH86; Condyline; Podocon-25; Podofilm; Podofilox; Podophyllotoxin, (5R-(5 alpha,5a alpha,8a alpha,9 alpha))-Isomer; Podophyllotoxin, (5R-(5 alpha,5a alpha,8a alpha,9 beta))-Isomer; Podophyllotoxin, (5R-(5 alpha,5a alpha,8a beta,9 alpha))-Isomer; Podophyllotoxin, (5R-(5 alpha,5a beta,8a alpha,9 beta))-Isomer; Warticon; Furo(3',4':6,7)naphtho(2,3- d)- 1,3- dioxol- 6(5aH)- one, 5,8,8a,9- tetrahydro- 9- hydroxy- 5- (3,4,5- trimethoxyphenyl)- , (5R-(5alpha,5abeta,8aalpha,9alpha))-

Pharmalogical Action Categories:

Antineoplastic Agents, Phytogenic
Keratolytic Agents
Tubulin Modulators

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthalenes: 18
        Tetrahydronaphthalenes: 1
        Podophyllotoxin: 562
      - Benzene Derivatives: 17
        Benzyl Compounds: 2
        Lignans: 1113
        Podophyllotoxin: 562
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthalenes: 18
    - Tetrahydronaphthalenes: 1
      - Podophyllotoxin: 562

4- (4- methylpiperazinyl)sulfonamido- 4'- O- demethyl- 4- desoxypodophyllotoxin

Bio-Agent Context: Research Results