picaridin

picaridin is the (R,S)-isomer; an insect repellent

Also Known As:

1-(1-methylpropoxycarbonyl)-2-(2-hydroxyethyl)piperidine; 2-(2-hydroxyethyl)-1-piperidinecarboxylic acid 1-methylpropyl ester; Bayrepel; KBR 3023; Saltidin; icaridin; sec-butyl 2-(2-hydroxyethyl)piperidine-1-carboxylate

Networked: 26 relevant articles (6 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperidines: 17
    - picaridin: 26

Experts

1.	Coosemans, Marc: 4 articles (01/2017 - 12/2014)
2.	Durnez, Lies: 4 articles (01/2017 - 12/2014)
3.	Heng, Somony: 4 articles (01/2017 - 12/2014)
4.	Sluydts, Vincent: 4 articles (01/2017 - 12/2014)
5.	Tho, Sochantha: 2 articles (01/2017 - 11/2015)
6.	Gryseels, Charlotte: 2 articles (10/2016 - 11/2015)
7.	Sochantha, Tho: 2 articles (10/2016 - 12/2014)
8.	Uk, Sambunny: 2 articles (10/2016 - 11/2015)
9.	Van Roey, Karel: 2 articles (10/2016 - 12/2014)
10.	Siv, Sovannaroth: 2 articles (11/2015 - 12/2014)

Related Diseases

1.	Bites and Stings (Sting) 11/17/2015 - "Repellents were made widely available and Picaridin repellent reduced 97% of mosquito bites. " 12/01/2014 - "The protective efficacy of two formulated picaridin repellents against mosquito bites, including arbovirus and malaria vectors, was evaluated in a field study in Cambodia. " 03/01/2004 - "On the basis of available evidence, KBR 3023 represents a promising alternative to DEET for personal protection against bites of these important vectors of disease in the Afrotropical region." 11/01/2011 - "Comparison among homemade repellents made with cloves, picaridin, andiroba, and soybean oil against Aedes aegypti bites." 12/15/2013 - "Applying insect repellent containing diethyltoluamide (DEET) 10% to 35% or picaridin 20% is the best method for preventing bites. "
2.	Malaria 10/01/2016 - "Efficacy of topical mosquito repellent (picaridin) plus long-lasting insecticidal nets versus long-lasting insecticidal nets alone for control of malaria: a cluster randomised controlled trial." 01/01/2017 - "Adverse reactions and abuse during mass use of picaridin were uncommon and generally mild, supporting the safety of the picaridin repellent for malaria control." 12/01/2014 - "Field evaluation of picaridin repellents reveals differences in repellent sensitivity between Southeast Asian vectors of malaria and arboviruses." 12/01/2014 - "The protective efficacy of two formulated picaridin repellents against mosquito bites, including arbovirus and malaria vectors, was evaluated in a field study in Cambodia. " 01/01/2017 - "Safety of a topical insect repellent (picaridin) during community mass use for malaria control in rural Cambodia."
3.	Body Weight (Weight, Body) 05/01/1999 - "Based on these results, KBR 3023, administered as described in this study at dose levels as high as 200 mg/kg body weight (the physical limit of dermal application for this compound), did not demonstrate any reproductive toxicity." 05/01/1999 - "Specifically, the adult rats (P generation) were fitted with Elizabethan collars, to reduce the likelihood of oral ingestion, and dermally administered either 0, 50, 100, or 200 mg KBR 3023/kg body weight throughout the study (5 d/week) beginning at the onset of the 10-week premating period and continuing through the mating, gestation, and lactation phases. " 12/20/1999 - "All in-life parameters, which included body weight, food consumption, clinical observations, survival, ophthalmology, clinical chemistry, hematology, and urinalysis, were unaffected by exposure to KBR 3023. " 12/20/1999 - "All in-life parameters, which included body weight, food consumption, clinical observations, survival, and hematology were unaffected by exposure to KBR 3023. " 12/20/1999 - "Relying upon the toxicology profile that emerged in the subchronic rat bioassay that was conducted using dermally applied dosages of 0, 80, 200, 500, and 1000 mg KBR 3023/kg body weight per day, it was determined, in concert with the EPA, that dermally applied dosages of 0, 50, 100, or 200 mg KBR 3023/kg body weight per day would be used in the conduct of all definitive forms of subchronic, chronic, and lifetime descriptive testing performed with the chemical. "
4.	Yellow Fever 01/01/2017 - "Our measurements showed that DEET provided significantly higher protection than picaridin provided against noninfected, host-seeking females of the southern house mosquito, Culex quinquefasciatus, and the yellow fever mosquito, Aedes aegypti. " 03/01/2004 - "We conducted laboratory tests to assess the sensitivity to the insect repellent 1-piperidinecarboxylic acid, 2-(2-hydroxyethyl)-, 1-methylpropylester (known as KBR 3023 or Picaridin, trade name Bayrepel) of West African strains of the yellow fever mosquito Aedes aegypti and of malaria vectors of the Anopheles gambiae complex, in comparison with the standard repellent N,N-diethyl-3-methyl-benzamide (DEET). "
5.	Allergic Contact Dermatitis 01/01/2005 - "Allergic contact dermatitis due to an insect repellent: double sensitization to picaridin and methyl glucose dioleate."

Related Drugs and Biologics

1.	DEET (DET)
2.	picaridin
3.	Insect Repellents
4.	ethyl- 3- (N- n- butyl- N- acetyl)aminopropionate
5.	Insecticides
6.	piperidine
7.	insect repellent M 3535
8.	potassium bromide
9.	Permethrin (Ambush)
10.	Sunscreening Agents (Sunscreens)

Related Therapies and Procedures

1.	Skin Cream