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TRA418

has both thromboxane A(2) receptor antagonistic and prostaglandlin I2 receptor agonistic activities; structure in first source

Also Known As:

(4-(2-(1,1-diphenylethylsulfanyl)ethyl)-3,4-dihydro-2H-benzo(1,4)oxazin-8-yloxy)actic acid N methyl-D-glucamime salt; TRA-418

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Oxazines: 9
    - TRA418: 1

Experts

1.	Kakiuchi, Takeharu: 1 article (11/2005)
2.	Matsuura, Hirotoshi: 1 article (11/2005)
3.	Tsukada, Hideo: 1 article (11/2005)
4.	Umemura, Kazuo: 1 article (11/2005)
5.	Yamada, Naohiro: 1 article (11/2005)

Related Diseases

1.

Stroke (Strokes)

11/01/2005 - "Our observations suggest that TRA-418 has neuroprotective action, as displayed in a primate model of stroke using PET monitoring."
11/01/2005 - "The aim of this study was to evaluate the neuroprotective effect of TRA-418, an antiplatelet agent, using PET in a monkey model of stroke. "
11/01/2005 - "PET study of the neuroprotective effect of TRA-418, an antiplatelet agent, in a monkey model of stroke."

Related Drugs and Biologics

1.	Neuroprotective Agents
2.	Platelet Aggregation Inhibitors (Antiplatelet Drugs)