HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

SY 21

a neuroprotective agent; a brutto-formula C27-H30-O15

Also Known As:

SY-21

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        SY 21: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        SY 21: 1

Experts

1.	Chen, Min: 1 article (11/2003)
2.	Hou, Xiao-Yu: 1 article (11/2003)
3.	Liu, Yong: 1 article (11/2003)
4.	Meng, Fan-Jie: 1 article (11/2003)
5.	Wang, Yao: 1 article (11/2003)
6.	Zhang, Guang-Yi: 1 article (11/2003)
7.	Zhang, Quan-Guang: 1 article (11/2003)

Related Diseases

1.	Brain Ischemia (Cerebral Ischemia) 11/07/2003 - "Possible mechanisms underlying the protective effects of SY-21, an extract of a traditional Chinese herb, on transient brain ischemia/reperfusion-induced neuronal death in rat hippocampus." 11/07/2003 - "Administration of SY-21 20 min before or 6 h after brain ischemia significantly increased the number of surviving hippocampal CA1 pyramidal cells in rats subjected to transient brain ischemia followed by 5 days of reperfusion. " 11/07/2003 - "We found that the increase in the tyrosine phosphorylation of NR2A induced by brain ischemia/reperfusion is suppressed by SY-21 administered 15 min before, or instantly after, brain ischemia. "
2.	Ischemia 11/07/2003 - "In order to investigate the possible mechanism of the neuroprotective action of SY-21, we examined the effects of SY-21 on the ischemia/reperfusion-induced increases in tyrosine phosphorylation of the NMDA receptor subunit 2A (NR2A) and on the interactions involving NR2A, PSD-95 and Src/Fyn. "

Related Drugs and Biologics

1.	N-Methyl-D-Aspartate Receptors (NMDA Receptors)
2.	Tyrosine (L-Tyrosine)