atraric acid

structure in first source; from the stem barks of Newbouldia laevis

Networked: 11 relevant articles (2 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Phenols: 677
        Hydroxybenzoates: 18
        atraric acid: 11
        Benzoates: 426
        Hydroxybenzoates: 18
        atraric acid: 11
- Carboxylic Acids: 973
  - Hydroxy Acids: 94
    - Hydroxybenzoates: 18
      - atraric acid: 11
  - Carbocyclic Acids
    - Benzoates: 426
      - Hydroxybenzoates: 18
        atraric acid: 11

Experts

1.	Baniahmad, Aria: 4 articles (01/2022 - 08/2009)
2.	Bartsch, Sophie: 2 articles (01/2022 - 11/2014)
3.	Grimm, Marc-Oliver: 2 articles (01/2022 - 11/2014)
4.	Roell, Daniela: 2 articles (01/2011 - 08/2009)
5.	Areche, Carlos: 1 article (12/2022)
6.	Bhat, Mamta: 1 article (12/2022)
7.	Conlan, Xavier A: 1 article (12/2022)
8.	Goel, Mayurika: 1 article (12/2022)
9.	Gupta, Manish: 1 article (12/2022)
10.	Kalra, Rishu: 1 article (12/2022)

Related Diseases

1.	Hyperpigmentation 12/15/2022 - "Atraric Acid Ameliorates Hyperpigmentation through the Downregulation of the PKA/CREB/MITF Signaling Pathway."
2.	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 01/30/2019 - "The bark of Prunus africana may contain atranorin, atraric acid, beta-sitosterol and its esters, ferulic acid and its esters, and N-butylbenzene sulfonamide, compounds that have been shown to improve the conditions of benign prostatic hyperplasia, enlarged prostate. "
3.	Ovarian Neoplasms (Ovarian Cancer) 12/01/2022 - "furfuracea and its polyphenolic compound, atraric acid as a promising candidate for ovarian cancer management." 12/01/2022 - "The results revealed that atraric acid showed significant activity against ovarian cancer cell line (PA-1) having GI50 at 16.42 µg/mL and moderate activity against the breast cancer cell line (MCF-7), having GI50 at 64.35 µg/mL. The results were further supported by in silico molecular docking studies of atraric acid with the epidermal growth factor receptor (EGFR) tyrosine kinase protein. "
4.	Breast Neoplasms (Breast Cancer) 12/01/2022 - "The results revealed that atraric acid showed significant activity against ovarian cancer cell line (PA-1) having GI50 at 16.42 µg/mL and moderate activity against the breast cancer cell line (MCF-7), having GI50 at 64.35 µg/mL. The results were further supported by in silico molecular docking studies of atraric acid with the epidermal growth factor receptor (EGFR) tyrosine kinase protein. "
5.	Prostatic Neoplasms (Prostate Cancer) 08/01/2009 - "The natural compound atraric acid is an antagonist of the human androgen receptor inhibiting cellular invasiveness and prostate cancer cell growth." 11/01/2014 - "Atraric acid (AA) inhibits the transactivation of the androgen receptor (AR) and androgen-mediated growth of AR-expressing human prostate cancer (PCa) cell lines. " 12/01/2022 - "In silico characterization of competing endogenous RNA network in castration-resistant prostate cancer cells in presence of the natural compound atraric acid using RNA-seq analysis." 01/01/2022 - "The natural compound atraric acid suppresses androgen-regulated neo-angiogenesis of castration-resistant prostate cancer through angiopoietin 2." 01/30/2011 - "The natural compounds atraric acid and N-butylbenzene-sulfonamide as antagonists of the human androgen receptor and inhibitors of prostate cancer cell growth."

Related Drugs and Biologics

1.	Sulfonamides
2.	Esters
3.	n-butylbenzene
4.	atranorin
5.	gamma-sitosterol (beta-sitosterol)
6.	ferulic acid (sodium ferulate)
7.	ErbB Receptors (EGF Receptor)
8.	Proteins (Proteins, Gene)
9.	Protein-Tyrosine Kinases (Tyrosine Kinase)
10.	Androgen Receptors (Androgen Receptor)

Related Therapies and Procedures

1.	Castration