6- diphenylmethyl- 5- (5- isopropyl- 2- methoxybenzylamino)- 1- azabicyclo(2.2.2)octane- 3- carboxylic acid
Also Known As:
CJ 12,255; CJ 12255; CJ-12,255; CJ-12255; CJ12,255; CJ12255
Networked: 4
relevant articles (0 outcomes,
0 trials/studies)
Bio-Agent Context: Research Results
Experts
| 1. | Pothoulakis, Charalabos:
4 articles
(11/2010 - 04/2006)
|
| 2. | Zhao, Dezheng:
4 articles
(11/2010 - 04/2006)
|
| 3. | Koon, Hon-Wai:
3 articles
(08/2008 - 04/2006)
|
| 4. | Moyer, Mary P:
3 articles
(08/2008 - 04/2006)
|
| 5. | Xu, Hua:
2 articles
(11/2010 - 08/2008)
|
| 6. | Zhan, Yanai:
2 articles
(02/2007 - 04/2006)
|
| 7. | Fazelbhoy, Zafeer:
1 article
(11/2010)
|
| 8. | Gerard, Norma:
1 article
(11/2010)
|
| 9. | Hing, Tressia:
1 article
(11/2010)
|
| 10. | Karagiannides, Iordanes:
1 article
(11/2010)
|
Related Diseases
| 1. | Colitis
02/06/2007
- " administration of CJ-12,255 for 5 days post-DSS suppressed Akt activation, exacerbated colitis, and enhanced apoptosis, and pharmacologic inhibition of Akt, either alone or together with CJ-12,255, produced a similar effect. " 04/15/2006
- " Lastly, COX-2 expression was elevated in colon of mice during experimental colitis, and this effect was normalized by administration of the NK-1R antagonist CJ-12,255. " 08/01/2008
- " Both the degree of angiogenesis and CCN1 expression were elevated in the colons of mice with dextran sodium sulfate-induced colitis, which was reduced by treatment with the NK-1R antagonist CJ-12255. "
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| 2. | Inflammation (Inflammations)
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| 3. | Fibrosis (Cirrhosis)
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