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(23R,24S)- 16,23- 16,24- diepoxy- 9,19- cyclolanostan- 3beta,15alpha,25- triol

structure in first source

Also Known As:

Cimigenol

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Greil, Richard: 1 article (02/2020)
2.	Jöhrer, Karin: 1 article (02/2020)
3.	Stuppner, Hermann: 1 article (02/2020)
4.	Çiçek, Serhat Sezai: 1 article (02/2020)
5.	Dai, Yan-Peng: 1 article (10/2018)
6.	Sun, Li-Li: 1 article (10/2018)
7.	Xia, Hong-Min: 1 article (10/2018)
8.	Fan, Yi: 1 article (01/2018)
9.	Li, Xiao: 1 article (01/2018)
10.	Wang, Wei: 1 article (01/2018)

Related Diseases

1.	Multiple Myeloma 02/11/2020 - "The variety of cimigenol derivatives, moreover, allowed a detailed discussion of their structure-activity relationships, not only for their effect on multiple myeloma cells but also with regard to previous studies on the cytotoxicity of black cohosh triterpenoids."
2.	Carcinogenesis 03/20/2003 - "Antitumor-promoting effects of cimigenol and related compounds on Epstein-Barr virus activation and two-stage mouse skin carcinogenesis."
3.	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 02/01/2023 - "Cimigenol depresses acute myeloid leukemia cells protected by breaking bone marrow stromal cells via CXCR4/SDF‑1α."
4.	Osteoporosis 10/01/2018 - "They are divided into types of cimigenol, hydroshengmanol, shengmanol, cimiacerogenin, acteol, 16, 23-diketo, foetidonol, dahurinol, etc. Cycloartane triterpenoids show many biological activities, such as cytotoxicity, anti-osteoporosis, antiviral, anti-inflammatory, anti-nucleoside transport, neuroprotective, anti-oxidant, antibacterial activities. "
5.	Neoplasms (Cancer) 01/01/2012 - "In the in vitro cytotoxicity evaluation of these compounds against 5 human cancer cell lines, cimigenol (8) exerted the most potent cytotoxic activity against SMMC-7721 (7.87 µM) and A-549 (12.16 µM), while cimiacerin B (9) also showed obvious cytotoxicity against the A-549 cell line, with an IC(50) value of 16.77 µM."

Related Drugs and Biologics

1.	Triterpenes
2.	Nucleosides
3.	Antiviral Agents (Antivirals)
4.	Antioxidants
5.	cycloartane