Ac-hE18A-NH(2)

dual domain peptide Ac-hE18A-NH(2), in which LRKLRKRLLR, (141-150 region of human apo E) covalently linked to a class A lipid-associating domain, is able to associate with apo B-containing lipoproteins

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Lipids: 114793
- Lipoproteins: 18361
  - Ac-hE18A-NH(2): 2
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Lipoproteins: 18361
    - Ac-hE18A-NH(2): 2
- Peptides: 82426
  - Peptide Fragments: 373
    - Ac-hE18A-NH(2): 2

Experts

1.	Anantharamaiah, G M: 2 articles (03/2013 - 12/2011)
2.	Garber, David W: 2 articles (03/2013 - 12/2011)
3.	Handattu, Shaila P: 2 articles (03/2013 - 12/2011)
4.	Mishra, Vinod K: 2 articles (03/2013 - 12/2011)
5.	Nayyar, Gaurav: 2 articles (03/2013 - 12/2011)
6.	Datta, Geeta: 1 article (03/2013)
7.	Keenum, Tamara D: 1 article (03/2013)
8.	Monroe, Candyce E: 1 article (03/2013)
9.	Palgunachari, Mayakonda N: 1 article (03/2013)
10.	Goldberg, Dennis: 1 article (12/2011)

Related Diseases

1.	Atherosclerosis 03/01/2013 - "However, peptide Ac-hE18A-NH(2) was significantly more effective in inhibiting atherosclerosis. "
2.	Hyperlipidemias (Hyperlipidemia) 12/01/2011 - "ApoE mimetics such as Ac-hE18A-NH(2) may therefore restore or replace ligands in genetically induced hyperlipidemias to enable reduction in atherogenic lipoproteins via HSPG even in the absence of functional low-density lipoprotein receptors. "

Related Drugs and Biologics

1.	Peptides (Polypeptides)
2.	Heparan Sulfate Proteoglycans (Heparan Sulfate Proteoglycan)
3.	LDL Receptors (LDL Receptor)
4.	Lipoproteins (Lipoprotein)
5.	Ligands
6.	Apolipoproteins E (ApoE)