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gaillardin

isolated from the aerial parts of Inula oculus-christi; structure in first source

Networked: 3 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Sesquiterpenes: 1370
      - gaillardin: 3
- Lactones: 1549
  - gaillardin: 3

Experts

1.	Abdolmohammadi, Mohammad Hossein: 2 articles (12/2021 - 12/2015)
2.	Fallahian, Faranak: 2 articles (12/2021 - 12/2015)
3.	Hamzeloo-Moghadam, Maryam: 2 articles (12/2021 - 12/2015)
4.	Irani, Shiva: 1 article (12/2021)
5.	Roozbehani, Maryam: 1 article (12/2021)
6.	Aghaei, Mahmoud: 1 article (12/2015)
7.	Atoofi, Azadeh: 1 article (03/2013)
8.	Irani, Mahboobeh: 1 article (03/2013)
9.	Moghadam, Maryam Hamzeloo: 1 article (03/2013)
10.	Mosaddegh, Mahmoud: 1 article (03/2013)

Related Diseases

1.	Neoplasms (Cancer) 03/01/2013 - "The results suggest gaillardin as a candidate for further studies in cancer therapy" 12/05/2021 - "This study was carried out to evaluate the anti-cancer properties of Gaillardin in gastric cancer cells and also its possible underlying mechanism. " 12/01/2015 - "Taken together, these results demonstrate that Gaillardin can inhibit proliferation of breast cancer cells via inducing mitochondrial apoptotic pathway and therefore, might be a promising molecule in cancer chemoprevention or chemotherapy. " 12/05/2021 - "Gaillardin, a sesquiterpene lactone isolated from Inula oculus-christi, seems to have great potential as an anti-cancer agent. "
2.	Stomach Neoplasms (Stomach Cancer) 12/05/2021 - "This study was carried out to evaluate the anti-cancer properties of Gaillardin in gastric cancer cells and also its possible underlying mechanism. " 12/05/2021 - "Gaillardin, a potent sesquiterpene lactone induces apoptosis via down-regulation of NF-κβ in gastric cancer cells, AGS and MKN45."
3.	Breast Neoplasms (Breast Cancer) 12/01/2015 - "The current study was therefore carried out to address the issue if Gaillardin is able to induce apoptosis in the breast cancer cell lines MCF-7 and MDA-MB-468 and to determine the underlying mechanism of its anticancer effects. " 12/01/2015 - "Taken together, these results demonstrate that Gaillardin can inhibit proliferation of breast cancer cells via inducing mitochondrial apoptotic pathway and therefore, might be a promising molecule in cancer chemoprevention or chemotherapy. " 12/01/2015 - "Molecular mechanism of apoptosis induction by Gaillardin, a sesquiterpene lactone, in breast cancer cell lines : Gaillardin-induced apoptosis in breast cancer cell lines."

Related Drugs and Biologics

1.	Sesquiterpenes
2.	Lactones

Related Therapies and Procedures

1.	Therapeutics
2.	Chemoprevention
3.	Drug Therapy (Chemotherapy)