herbal compound 861

contains 10 herbs with Salvia miltiorrhiza as its chief component; also contains Astragalus membranaceous, Spatholobus suberectus, and glycyrrhizin; may be useful for treatment of liver cirrhosis and suppressing hepatocarcinogenesis

Also Known As:

861 (herbal cpd)

Networked: 4 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Complex Mixtures: 1906
- Biological Products
  - Plant Preparations: 622
    - Plant Extracts: 3916
      - Chinese Herbal Drugs: 73
        herbal compound 861: 4
Pharmaceutical Preparations
- Chinese Herbal Drugs: 73
  - herbal compound 861: 4

Experts

1.	Chi, Cheng: 1 article (02/2018)
2.	Cui, Li-Jian: 1 article (02/2018)
3.	Hou, Fei: 1 article (02/2018)
4.	Li, Chun-Yun: 1 article (02/2018)
5.	Liu, Rui-Xia: 1 article (02/2018)
6.	Liu, Xiao-Ya: 1 article (02/2018)
7.	Yin, Cheng-Hong: 1 article (02/2018)
8.	Yu, Xiao-Zheng: 1 article (02/2018)
9.	Qiao, Yan-Jiang: 1 article (10/2004)
10.	Tan, Xue-Hai: 1 article (10/2004)

Related Diseases

1.	Portal Hypertension 05/01/2002 - "To study the effect of herbal compound 861 (HB861) on expression and activity of nitric oxide synthase (NOS) in hepatic stellate cells (HSC), and to explore the feasibility of its application in preventing and treating the early portal hypertension. "
2.	Fibrosis (Cirrhosis) 02/05/2018 - "Herbal compound 861 prevents hepatic fibrosis by inhibiting the TGF-β1/Smad/SnoN pathway in bile duct-ligated rats." 02/05/2018 - "This study was to evaluate the effects of herbal compound 861 (Cpd861) on ski-related novel protein N (SnoN) and transforming growth factor-β1 (TGF-β1) /Smad signaling in rats with bile duct ligation (BDL)-induced hepatic fibrosis, and to explore the mechanisms of Cpd861 on hepatic fibrosis. "
3.	Liver Cirrhosis (Hepatic Cirrhosis) 12/01/2002 - "[The effect of herbal compound 861 on mRNA levels of MMP-2 and its activities in experimental rats liver fibrosis]."
4.	Carcinoma (Carcinomatosis) 10/01/2004 - "To investigate the effects of herbal compound 861 (Cpd 861) on cell proliferation in human hepatic stellate cells (LX-2) and human hepatocellular liver carcinoma cells (HepG2), and expression of alpha-smooth muscle actin (alpha-SMA) in LX-2 cells. "

Related Drugs and Biologics

1.	Nitric Oxide Synthase (NO Synthase)
2.	Proteins (Proteins, Gene)
3.	Messenger RNA (mRNA)

Related Therapies and Procedures

1.	Ligation