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dihydroergosine

is the principal toxic alkaloid produced by sorghum ergot (Claviceps africana)

Also Known As:

DHES cpd

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Ergot Alkaloids: 208
    - Ergotamines: 26
      - dihydroergosine: 2
- Fused-Ring Heterocyclic Compounds
  - 4 or More Rings Heterocyclic Compounds
    - Ergotamines: 26
      - dihydroergosine: 2

Experts

1.	Blaney, B J: 1 article (08/2010)
2.	Boucher, B D: 1 article (08/2010)
3.	Ryley, M J: 1 article (08/2010)

Related Diseases

1.	Tremor (Tremors) 01/01/1990 - "While 8-OH-DPAT alone produced all behavioral components of the 5-HT syndrome, dihydroergosine or imipramine alone even at very high doses never produced tremor or a more intensive forepaw padding as seen when these drugs were given in combination with pargyline and 5-HTP. "
2.	Hyperthermia 08/01/2010 - "Sorghum ergot produces dihydroergosine (DHES) and related alkaloids, which cause hyperthermia in cattle. "

Related Drugs and Biologics

1.	8-Hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT)
2.	Serotonin (5 Hydroxytryptamine)
3.	Pargyline (Pargyline Hydrochloride)
4.	Imipramine (Janimine)
5.	5-Hydroxytryptophan (5 Hydroxytryptophan)
6.	Alkaloids