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(1'R,5R,6R)- 3- (4- amino- 1,1- dimethyl- butyl)- 6- (1'- hydroxyethyl)oxapenem- 3- carboxylate
oxapenem compound which possesses potent beta-lactamase-inhibitory properties; structure in first source
Also Known As:
AM-112; AM112
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amides: 2428
Lactams: 2198
(1'R,5R,6R)-3-(4-amino-1,1-dimethyl-butyl)-6-(1'-hydroxyethyl)oxapenem-3-carboxylate: 1
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Lactams: 2198
(1'R,5R,6R)-3-(4-amino-1,1-dimethyl-butyl)-6-(1'-hydroxyethyl)oxapenem-3-carboxylate: 1
Experts
1.
Jamieson, Conor E
: 1 article (05/2003)
2.
Lambert, Peter A
: 1 article (05/2003)
3.
Simpson, Iain N
: 1 article (05/2003)
Related Diseases
1.
Sepsis (Septicemia)
05/01/2003 - "
Protection of ceftazidime with AM-112 was maintained against Enterobacter cloacae P99 and Klebsiella pneumoniae SHV-5 in a murine intraperitoneal sepsis model.
"
2.
Body Weight (Weight, Body)
05/01/2003 - "
pneumoniae SHV-5 was reduced from >100 and 160 mg/kg of body weight to 2 and 33.6 mg/kg, respectively, when it was combined with AM-112 at a 1:1 ratio.
"
Related Drugs and Biologics
1.
Ceftazidime (Fortum)