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peptide NK-2

a synthetic potent peptide antibiotic derived from NK-lysin

Also Known As:

NK-2 peptide

Networked: 5 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - peptide NK-2: 5

Experts

1.	Andrä, Jörg: 3 articles (01/2017 - 11/2005)
2.	Gay, Cyril G: 1 article (01/2021)
3.	Kim, Woo H: 1 article (01/2021)
4.	Lee, Youngsub: 1 article (01/2021)
5.	Lillehoj, Hyun S: 1 article (01/2021)
6.	Park, Inkyung: 1 article (01/2021)
7.	Przybyszewski, Chris: 1 article (01/2021)
8.	Wickramasuriya, Samiru S: 1 article (01/2021)
9.	van Oosterwijk, Jolieke G: 1 article (01/2021)
10.	Wilms, Dominik: 1 article (01/2017)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2017 - "Instead, it is suggested that the level of membrane surface-exposed phosphatidylserine is of crucial importance for the activity of peptide NK-2 and enhanced variants thereof in terms of their cancer cell selectivity, the overall efficacy, as well as the underlying mode of action and kinetics. " 04/15/2013 - "We postulated that NK-lysin derived cationic peptide NK-2 might discriminate and preferentially eliminate P-gp over-expressing cancer cells. " 01/01/2017 - "Here, we investigated the cytotoxicity of peptide NK-2 and structurally improved anti-cancer variants thereof against two patient-derived colorectal cancer cell lines, exposing high and low levels of phosphatidylserine on their cell surfaces, respectively. " 11/07/2005 - "The NK-lysin derived peptide NK-2 preferentially kills cancer cells with increased surface levels of negatively charged phosphatidylserine."
2.	Colorectal Neoplasms (Colorectal Cancer) 01/01/2017 - "Here, we investigated the cytotoxicity of peptide NK-2 and structurally improved anti-cancer variants thereof against two patient-derived colorectal cancer cell lines, exposing high and low levels of phosphatidylserine on their cell surfaces, respectively. "
3.	Infections 01/01/2021 - "Oral Delivery of Bacillus subtilis Expressing Chicken NK-2 Peptide Protects Against Eimeria acervulina Infection in Broiler Chickens."
4.	Coccidiosis 05/01/2023 - "Orally delivered Bacillus subtilis expressing chicken NK-2 peptide stabilizes gut microbiota and enhances intestinal health and local immunity in coccidiosis-infected broiler chickens."

Related Drugs and Biologics

1.	Phosphatidylserines
2.	NK-lysin