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1- (((3- hydroxy- 1- adamantyl)amino)acetyl)- 2- cyanopyrrolidine (LAF237)

inhibits dipeptidyl peptidase IV metabolism of GLP-1 to provide antihyperglycemic effect; structure in first source
Also Known As:
LAF237; HAAA-2-cyanopyrrolidine; LAF 237; LAF-237
Networked: 8 relevant articles (3 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Jin, Heung Yong: 1 article (02/2012)
2. Kim, Won: 1 article (02/2012)
3. Liu, Wei Jing: 1 article (02/2012)
4. Liu, Yu Ning: 1 article (02/2012)
5. Park, Sung Kwang: 1 article (02/2012)
6. Park, Tae Sun: 1 article (02/2012)
7. Shao, Yi Ming: 1 article (02/2012)
8. Xie, Shu Hua: 1 article (02/2012)
9. Cao, Feng: 1 article (01/2012)
10. Li, Weijie: 1 article (01/2012)

Related Diseases

1. Type 2 Diabetes Mellitus (MODY)
2. Proteinuria
3. Albuminuria
4. Neoplasms (Cancer)
5. Inflammation (Inflammations)

Related Drugs and Biologics

1. Vildagliptin
2. Metformin (Glucophage)
3. Dipeptidyl-Peptidase IV Inhibitors
4. Creatinine
5. Albumins
6. Angiotensin II Type 1 Receptor Blockers
7. Valsartan (Vals)
8. Valine (L-Valine)
9. Peptide Hydrolases (Proteases)
10. Dipeptidyl-Peptidases and Tripeptidyl-Peptidases

Related Therapies and Procedures

1. Glycemic Control