rat atrial natriuretic peptide

rat natriuretic peptide precursor type A, ref seq NM_012612; see also non-organism-specific peptides, NATRIUTRETIC PEPTIDES.

Also Known As:

atrial natriuretic peptide, rat; NPPA protein, rat; atrial natriuretic factor precursor, rat; atrial natriuretic factor, rat; atrial natriuretic peptide (1-28), rat; atrial natriuretic peptide precursor, rat; natriuretic peptide precursor type A, rat; rANP (1-28); rat ANF (99-126); rat ANF prohormone (99-126)

Networked: 11 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Barbato, Daniela: 1 article (01/2007)
2.	Brunetti, Ercole: 1 article (01/2007)
3.	De Paolis, Paola: 1 article (01/2007)
4.	Ganten, Ursula: 1 article (01/2007)
5.	Lombardi, Alessia: 1 article (01/2007)
6.	Marchitti, Simona: 1 article (01/2007)
7.	Nobili, Valerio: 1 article (01/2007)
8.	Rubattu, Speranza: 1 article (01/2007)
9.	Tarasi, David: 1 article (01/2007)
10.	Volpe, Massimo: 1 article (01/2007)

Related Diseases

1.	Body Weight (Weight, Body) 01/01/1991 - "Renal clearance studies were conducted in conscious, chronically catheterized obese and lean Zucker rats to investigate the natriuretic responses to i) acute IV infusion of isotonic NaCl = 5% of total body weight and ii) IV infusion of alpha rat atrial natriuretic peptide (ANP) in a dose of 300 ng/kg/min. In the baseline state, arterial blood pressure (BP) was significantly higher in obese vs lean rats. " 11/01/1990 - "Since renal mechanisms by which ANP induces a natriuresis remain unclear, the effects of the infusion of 0.03 micrograms/min/kg body weight of rANP 1-28 into the right renal artery (via a very thin catheter inserted into the suprarenal artery) were studied in anesthetized rats using lithium clearance to monitor proximal tubular function. "
2.	Vascular Remodeling 01/01/2007 - "Role of a molecular variant of rat atrial natriuretic Peptide gene in vascular remodeling."
3.	Nephritis 02/01/1987 - "Renal effects of synthetic rat-atrial natriuretic peptide in nephron-reduced rats with nephrotoxic nephritis."
4.	Neoplasms (Cancer) 02/15/1988 - "Native rat atrial natriuretic peptide (NANP) was shown to bind with high affinity and to increase intracellular levels of cGMP in cultured rat Leydig tumor cells. "
5.	Pulmonary Hypertension 09/01/1991 - "2. Continuous intravenous infusion of two doses of synthetic rat atrial natriuretic peptide, 300 ng/h per rat (0.10 pmol/h per rat) and 800 ng/h per rat (0.28 pmol/h per rat), attenuated the development of pulmonary hypertension in rats exposed to chronic hypoxia (fractional concentration of oxygen in inspired air = 10%) for 7 days: (i) the pulmonary artery pressure (mean +/- SD) in the vehicle-treated hypoxic group was 45 +/- 6 mmHg compared with 28 +/- 6 mmHg in the vehicle-treated normotoxic group (n = 8, P less than 0.001); (ii) treatment with atrial natriuretic peptide in normoxia did not alter the pulmonary artery pressure, systemic blood pressure or heart rate; (iii) treatment with atrial natriuretic peptide in hypoxia resulted in a lower pulmonary artery pressure in the group treated with 800 ng of atrial natriuretic peptide/h per rat (38 +/- 8 mmHg, P less than 0.05 compared with the vehicle-treated hypoxic group) without affecting the systemic blood pressure or heart rate. "

Related Drugs and Biologics

1.	Atrial Natriuretic Factor (ANF)
2.	porcine brain natriuretic peptide
3.	C-Type Natriuretic Peptide (Peptide, C-Type Natriuretic)
4.	Brain Natriuretic Peptide (Natrecor)
5.	Vasopressins (Vasopressin)
6.	Tretinoin (Retinoic Acid)
7.	Sodium
8.	Oxygen (Dioxygen)
9.	Lithium
10.	Guanylate Cyclase (Guanylyl Cyclase)

Related Therapies and Procedures

1.	Catheters
2.	Intravenous Infusions