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protoneodioscin

a furostanol saponin from the rhizomes of Dioscorea collettii (Dioscoreaceae); structure in first source

Also Known As:

NSC-698789; NSC698789

Networked: 1 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycosides: 2119
  - Saponins: 2867
    - protoneodioscin: 1
Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Cholestanes
      - Sterols: 2245
        protoneodioscin: 1
Lipids: 114793
- Membrane Lipids: 1591
  - Sterols: 2245
    - protoneodioscin: 1

Experts

1.	Hu, Ke: 1 article (09/2002)
2.	Yao, Xinsheng: 1 article (09/2002)

Related Diseases

1.	Neoplasms (Cancer) 09/01/2002 - "Our studies showed that protoneodioscin is cytotoxic against most cell lines from leukemia and solid tumors in the NCI's (National Cancer Institute, USA) anticancer drug screen. " 09/01/2002 - "Protoneodioscin (NSC-698789) is a furostanol saponin isolated from the rhizomes of Dioscorea collettii var. hypoglauca (Dioscoreaceae), a Chinese herbal remedy for cancer treatment. " 09/01/2002 - "The cytotoxicity of protoneodioscin (NSC-698789), a furostanol saponin from the rhizomes of Dioscorea collettii var. hypoglauca, against human cancer cells in vitro." 09/01/2002 - "Leukemia, CNS cancer, and prostate cancer are the most sensitive subpanels to protoneodioscin, while melanoma, ovarian cancer, and renal cancer are less sensitive. "
2.	Leukemia 09/01/2002 - "Our studies showed that protoneodioscin is cytotoxic against most cell lines from leukemia and solid tumors in the NCI's (National Cancer Institute, USA) anticancer drug screen. " 09/01/2002 - "Leukemia, CNS cancer, and prostate cancer are the most sensitive subpanels to protoneodioscin, while melanoma, ovarian cancer, and renal cancer are less sensitive. "
3.	Prostatic Neoplasms (Prostate Cancer) 09/01/2002 - "Leukemia, CNS cancer, and prostate cancer are the most sensitive subpanels to protoneodioscin, while melanoma, ovarian cancer, and renal cancer are less sensitive. "
4.	Ovarian Neoplasms (Ovarian Cancer) 09/01/2002 - "Leukemia, CNS cancer, and prostate cancer are the most sensitive subpanels to protoneodioscin, while melanoma, ovarian cancer, and renal cancer are less sensitive. "
5.	Melanoma (Melanoma, Malignant) 09/01/2002 - "Leukemia, CNS cancer, and prostate cancer are the most sensitive subpanels to protoneodioscin, while melanoma, ovarian cancer, and renal cancer are less sensitive. "

Related Drugs and Biologics

1.	Saponins