phenoxodiol

08/01/2010 - "An in vivo model confirmed the potential therapeutic efficacy of Phenoxodiol when administered orally to tumor bearing mice. "
01/01/2012 - "The cellular potency of compounds 7e and 12h were found to have greater in vitro inhibitory activities than phenoxodiol, the parental compound currently in late-stage clinical trials for the treatment of cancer. "
02/03/2011 - "This study reports the pharmacokinetics of phenoxodiol in patients with cancer. "
02/24/2009 - "Phenoxodiol is a novel isoflav-3-ene, currently undergoing clinical trials, that has a broad in vitro activity against a number of human cancer cell lines. "
10/01/2006 - "Phase I and pharmacokinetic study of weekly NV06 (Phenoxodiol), a novel isoflav-3-ene, in patients with advanced cancer."

01/01/2008 - "In this chapter, we discuss the role of apoptosis in ovarian cancer and the use of phenoxodiol as a model for the regulation of apoptosis and potential use as chemosensitizer for chemoresistant ovarian cancer cells."
06/01/2006 - "In this review, the current understanding of the mechanism of action of phenoxodiol, its potential clinical application for the treatment of ovarian cancer and the concept of chemosensitization are discussed."
06/01/2006 - "Phenoxodiol, a novel approach for the treatment of ovarian cancer."
04/01/2004 - "Phenoxodiol offers hope for ovarian cancer."
01/26/2007 - "Phenoxodiol causes XIAP degradation and chemotherapy sensitization in ovarian cancer. "

08/01/2010 - "Although a precise target for Phenoxodiol has not been identified, these data contribute to our understanding of the mechanism by which this drug promotes cell death in prostate cancer cells, and warrants the continued clinical development of Phenoxodiol as a therapeutic for the treatment of metastatic prostate cancer."
08/01/2010 - "In this study we tested the effects of Phenoxodiol against prostate cancer cell lines. "
01/01/2014 - "Three prostate cancer cell lines-LNCaP, DU145, and PC3 were cultured in vitro, and then treated with phenoxodiol (10 μM and 30 μM) for 24 and 48 h. "
01/01/2014 - "The effects of phenoxodiol on the cell cycle of prostate cancer cell lines."
03/01/2012 - "These data warrant the further investigation of phenoxodiol as a potential treatment for prostate cancer."

10/01/2018 - "A panel of renal cancer cells (769-P, 786-O, Caki-2) was treated with phenoxodiol in vitro, and the efficacy of treatment was evaluated. "
10/01/2018 - "Phenoxodiol inhibited Akt pathway and induced apoptosis of renal cancer cells. "
10/01/2018 - "MTS assay results showed that phenoxodiol decreased renal cancer viability in a dose-dependent manner. "
10/01/2018 - "Evaluation of Therapeutic Potential of Phenoxodiol, a Novel Isoflavone Analog, in Renal Cancer Cells."
10/01/2018 - "In the present study, the antineoplastic activity and mechanism of action of phenoxodiol, a novel isoflavone analog, was investigated in renal cancer cells. "

07/08/2005 - "An in vitro coculture model of prostate cancer cells (LNCaP) with human osteoblasts (hFOB) was utilized to define the efficacy of the tNOX inhibitors EGCg, capsaicin, Capsibiol-T and phenoxodiol against bone metastasis of prostate cancer alone and in combination with Taxol and cisplatin. "