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1- ((1- (3- acetoxy- 2,2- dimethylpropyl)- 7- chloro- 5- (2,3- dimethoxyphenyl)- 2- oxo- 1,2,3,5- tetrahydro- 4,1- benzoxazepin- 3- yl)acetyl)piperidine- 4- acetic acid

inhibits squalene synthase; structure in first source
Also Known As:
(1-(2-(1-(2-carboxyoxy-1,1-dimethylethyl)-7-chloro-5-(2,3-dimethoxyphenyl)-2-oxo-1,2,3,5-tetrahydrobenzo(e)(1,4)oxazepin-3-yl)acetyl)piperidin-4-yl)acetic acid; TAK 475; TAK-475; TAK475; lapaquistat
Networked: 9 relevant articles (2 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Nishimoto, Tomoyuki: 4 articles (08/2007 - 04/2003)
2. Ishikawa, Eiichiro: 3 articles (08/2007 - 04/2003)
3. Tozawa, Ryuichi: 3 articles (08/2007 - 07/2003)
4. Amano, Yuichiro: 3 articles (12/2003 - 04/2003)
5. Imura, Yoshimi: 3 articles (12/2003 - 04/2003)
6. Sugiyama, Yasuo: 3 articles (12/2003 - 04/2003)
7. Marcuzzi, Annalisa: 1 article (01/2021)
8. Melloni, Elisabetta: 1 article (01/2021)
9. Rimondi, Erika: 1 article (01/2021)
10. Secchiero, Paola: 1 article (01/2021)

Related Diseases

1. Myotoxicity
2. Dyslipidemias (Dyslipidemia)
3. Mevalonate Kinase Deficiency
4. Atherosclerotic Plaque (Atheroma)
5. Myocardial Infarction

Related Drugs and Biologics

1. Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)
2. Farnesyl-Diphosphate Farnesyltransferase (Squalene Synthase)
3. Acetates (Acetic Acid Esters)
4. Lipids
5. Acids
6. cerivastatin (Kazak)

Related Therapies and Procedures

1. Therapeutics