5-iodo-4'-thio-2'-deoxyuridine
structure in first source
Also Known As:
(123)I-ITdU; (125)I-ITdU; 5-123I-iodo-4'-thio-2'-deoxyuridine; ITdU cpd
Networked: 4
relevant articles (0 outcomes,
0 trials/studies)
Bio-Agent Context: Research Results
Experts
1. | Morgenroth, Agnieszka:
3 articles
(01/2014 - 06/2007)
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2. | Zlatopolskiy, Boris D:
3 articles
(01/2014 - 06/2007)
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3. | Mottaghy, Felix M:
2 articles
(01/2014 - 10/2011)
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4. | Vogg, Andreas T J:
2 articles
(01/2014 - 06/2007)
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5. | Glatting, Gerhard:
2 articles
(10/2011 - 06/2007)
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6. | Reske, Sven N:
2 articles
(10/2011 - 06/2007)
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7. | Oedekoven, Caroline:
1 article
(01/2014)
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8. | Siluschek, Monika:
1 article
(01/2014)
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9. | Al-Momani, Ehab:
1 article
(10/2011)
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10. | Dinger, Cornelia:
1 article
(10/2011)
|
Related Diseases
1. | Neoplasms (Cancer)
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2. | Multiple Myeloma
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3. | Leukemia
06/01/2007
- " This finding indicates that (123)I-ITdU breaks resistance to beta-irradiation, gamma-irradiation, and doxorubicin in leukemia cells. " 06/01/2007
- " In addition, (123)I-ITdU induced comparable apoptotic cell death (>90%) in sensitive parental leukemia cells and in leukemia cells resistant to beta-irradiation, gamma-irradiation, or doxorubicin at activities of 1.2, 4.1, 12.4, and 41.3 MBq/mL after 72 h. " 06/01/2007
- " Cellular uptake, metabolic stability, DNA incorporation of (123)I-ITdU, and the effect of the thymidylate synthase (TS) inhibitor 5-fluoro-2'-deoxyuridine (FdUrd) were determined in HL60 leukemia cells. "
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Related Drugs and Biologics
Related Therapies and Procedures