human Neu3 protein

RefSeq NM_006656

Also Known As:

Neu3 protein, human; human plasma membrane-associated sialidase; plasma membrane-associated ganglioside sialidase Neu3, human; sialidase 3 (membrane sialidase), human

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Glycoside Hydrolases: 871
      - Neuraminidase: 4879
        human Neu3 protein: 5

Experts

1.	Miyagi, Taeko: 3 articles (08/2010 - 03/2006)
2.	Yamaguchi, Kazunori: 3 articles (08/2010 - 03/2006)
3.	Guo, Baofeng: 1 article (12/2011)
4.	Li, Na: 1 article (12/2011)
5.	Li, Xiaojie: 1 article (12/2011)
6.	Li, Yang: 1 article (12/2011)
7.	Liang, Zuowen: 1 article (12/2011)
8.	Shao, Chen: 1 article (12/2011)
9.	Shao, Yueting: 1 article (12/2011)
10.	Wang, Bo: 1 article (12/2011)

Related Diseases

1.	Colonic Neoplasms (Colon Cancer) 04/01/2009 - "Human plasma membrane-associated sialidase (NEU3) specifically hydrolyzes gangliosides, and it is up-regulated in colon cancer and plays an essential role in the expression of malignant phenotypes. " 03/15/2006 - "We have found previously that human plasma-membrane-associated sialidase (NEU3), a key glycosidase for ganglioside degradation, was markedly up-regulated in human colon cancers, with an involvement in suppression of apoptosis. "
2.	Carcinogenesis 08/15/2010 - "Gene expression of the human plasma membrane-associated sialidase (NEU3), a key enzyme for ganglioside degradation, is relatively high in brain and is modulated in response to many cellular processes, including neuronal cell differentiation and tumorigenesis. "
3.	Prostatic Neoplasms (Prostate Cancer) 12/16/2011 - "Effects of a human plasma membrane-associated sialidase siRNA on prostate cancer invasion."
4.	Neoplasms (Cancer) 04/12/2007 - "Human plasma membrane-associated sialidase (NEU3), a key enzyme for ganglioside degradation, is markedly upregulated in human cancers, leading to apoptosis suppression. "

Related Drugs and Biologics

1.	Gangliosides
2.	Enzymes
3.	Small Interfering RNA (siRNA)
4.	Glycoside Hydrolases (Endoglycosidases)