1,4,7,10-tetraazacyclododecane 1,4,7,10-tetraacetic acid (ReO- acetyl(Cys(3,4,10),Phe(7),Arg(7))alpha- MSH(3- 13))

structure in first source

Also Known As:

DOTA-ReCCMSH(Arg(11))

Networked: 2 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Peptide Hormones: 1347
    - Pituitary Hormones: 601
      - Anterior Pituitary Hormones: 187
        Pro-Opiomelanocortin: 1936
        alpha-MSH: 968
        1,4,7,10-tetraazacyclododecane 1,4,7,10-tetraacetic acid (ReO-acetyl(Cys(3,4,10),Phe(7),Arg(7))alpha-MSH(3-13)): 2
        Melanocortins: 946
        Melanocyte-Stimulating Hormones: 1119
        alpha-MSH: 968
        1,4,7,10-tetraazacyclododecane 1,4,7,10-tetraacetic acid (ReO-acetyl(Cys(3,4,10),Phe(7),Arg(7))alpha-MSH(3-13)): 2
    - Hypothalamic Hormones: 68
      - Pro-Opiomelanocortin: 1936
        alpha-MSH: 968
        1,4,7,10-tetraazacyclododecane 1,4,7,10-tetraacetic acid (ReO-acetyl(Cys(3,4,10),Phe(7),Arg(7))alpha-MSH(3-13)): 2
        Melanocortins: 946
        Melanocyte-Stimulating Hormones: 1119
        alpha-MSH: 968
        1,4,7,10-tetraazacyclododecane 1,4,7,10-tetraacetic acid (ReO-acetyl(Cys(3,4,10),Phe(7),Arg(7))alpha-MSH(3-13)): 2
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Nerve Tissue Proteins: 2
    - Neuropeptides: 6772
      - Melanocyte-Stimulating Hormones: 1119
        alpha-MSH: 968
        1,4,7,10-tetraazacyclododecane 1,4,7,10-tetraacetic acid (ReO-acetyl(Cys(3,4,10),Phe(7),Arg(7))alpha-MSH(3-13)): 2
      - Hypothalamic Hormones: 68
        Pro-Opiomelanocortin: 1936
        alpha-MSH: 968
        1,4,7,10-tetraazacyclododecane 1,4,7,10-tetraacetic acid (ReO-acetyl(Cys(3,4,10),Phe(7),Arg(7))alpha-MSH(3-13)): 2
        Melanocortins: 946
        Melanocyte-Stimulating Hormones: 1119
        alpha-MSH: 968
        1,4,7,10-tetraazacyclododecane 1,4,7,10-tetraacetic acid (ReO-acetyl(Cys(3,4,10),Phe(7),Arg(7))alpha-MSH(3-13)): 2
- Peptides: 82426
  - Neuropeptides: 6772
    - Melanocyte-Stimulating Hormones: 1119
      - alpha-MSH: 968
        1,4,7,10-tetraazacyclododecane 1,4,7,10-tetraacetic acid (ReO-acetyl(Cys(3,4,10),Phe(7),Arg(7))alpha-MSH(3-13)): 2
    - Hypothalamic Hormones: 68
      - Pro-Opiomelanocortin: 1936
        alpha-MSH: 968
        1,4,7,10-tetraazacyclododecane 1,4,7,10-tetraacetic acid (ReO-acetyl(Cys(3,4,10),Phe(7),Arg(7))alpha-MSH(3-13)): 2
        Melanocortins: 946
        Melanocyte-Stimulating Hormones: 1119
        alpha-MSH: 968
        1,4,7,10-tetraazacyclododecane 1,4,7,10-tetraacetic acid (ReO-acetyl(Cys(3,4,10),Phe(7),Arg(7))alpha-MSH(3-13)): 2
  - Peptide Hormones: 1347
    - Pituitary Hormones: 601
      - Anterior Pituitary Hormones: 187
        Pro-Opiomelanocortin: 1936
        alpha-MSH: 968
        1,4,7,10-tetraazacyclododecane 1,4,7,10-tetraacetic acid (ReO-acetyl(Cys(3,4,10),Phe(7),Arg(7))alpha-MSH(3-13)): 2
        Melanocortins: 946
        Melanocyte-Stimulating Hormones: 1119
        alpha-MSH: 968
        1,4,7,10-tetraazacyclododecane 1,4,7,10-tetraacetic acid (ReO-acetyl(Cys(3,4,10),Phe(7),Arg(7))alpha-MSH(3-13)): 2
    - Hypothalamic Hormones: 68
      - Pro-Opiomelanocortin: 1936
        alpha-MSH: 968
        1,4,7,10-tetraazacyclododecane 1,4,7,10-tetraacetic acid (ReO-acetyl(Cys(3,4,10),Phe(7),Arg(7))alpha-MSH(3-13)): 2
        Melanocortins: 946
        Melanocyte-Stimulating Hormones: 1119
        alpha-MSH: 968
        1,4,7,10-tetraazacyclododecane 1,4,7,10-tetraacetic acid (ReO-acetyl(Cys(3,4,10),Phe(7),Arg(7))alpha-MSH(3-13)): 2
Organic Chemicals: 133
- Organometallic Compounds: 64
  - 1,4,7,10-tetraazacyclododecane 1,4,7,10-tetraacetic acid (ReO-acetyl(Cys(3,4,10),Phe(7),Arg(7))alpha-MSH(3-13)): 2

Experts

1.	Lewis, Jason S: 2 articles (01/2007 - 04/2005)
2.	Miao, Yubin: 2 articles (01/2007 - 04/2005)
3.	Quinn, Thomas P: 2 articles (01/2007 - 04/2005)
4.	Welch, Michael J: 2 articles (01/2007 - 04/2005)
5.	Butcher, Clayton: 1 article (01/2007)
6.	Gallazzi, Fabio: 1 article (01/2007)
7.	Wei, Lihui: 1 article (01/2007)
8.	McQuade, Paul: 1 article (04/2005)
9.	Yoo, Jeongsoo: 1 article (04/2005)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2007 - "Biodistribution studies showed high and rapid receptor-mediated tumor uptake with values similar to those reported for (64)Cu- and (86)Y-labeled DOTA-ReCCMSH(Arg(11)). " 04/21/2005 - "In both cases a subset of animals were co-injected with 20 microg of DOTA-ReCCMSH(Arg(11)) to determine if tumor concentration was receptor mediated. "
2.	Melanoma (Melanoma, Malignant) 04/21/2005 - "The goal of this current study was to label DOTA-ReCCMSH(Arg(11)) with beta(+)-emitting radionuclides, to determine if the high sensitivity of positron emission tomography (PET) imaging would aid in the detection of malignant melanoma. " 04/21/2005 - "The data obtained suggests that DOTA-ReCCMSH(Arg(11)), when labeled with beta(+)-emitting radionuclides, has the potential for early detection of malignant melanoma by exploiting the sensitivity and high resolution of PET."

Related Drugs and Biologics

1.	Radioisotopes (Radionuclides)