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9-methoxycanthin-6-one

from roots of Eurycoma longifolia (Simaroubaceae)

Also Known As:

9-methoxy-canthin-6-one

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Amin, Nor Datiakma Mat: 1 article (01/2022)
2.	Hassan, Nor Hasnida: 1 article (01/2022)
3.	Jauri, Muhammad Haffiz: 1 article (01/2022)
4.	Ling, Sui Kiong: 1 article (01/2022)
5.	Sallehudin, Nor Jannah: 1 article (01/2022)
6.	Yunos, Nurhanan Murni: 1 article (01/2022)
7.	Bach, Tran The: 1 article (07/2013)
8.	Cuong, Nguyen Manh: 1 article (07/2013)
9.	Duc, Ho Viet: 1 article (07/2013)
10.	Duong, Nguyen Thanh: 1 article (07/2013)

Related Diseases

1.	Neoplasms (Cancer) 01/18/2022 - "These findings may provide a new insight on the mechanisms of action of 9-methoxycanthin-6-one in exerting its anti-cancer effects in vitro." 01/18/2022 - "The In Vitro Anti-Cancer Activities and Mechanisms of Action of 9-Methoxycanthin-6-one from Eurycoma longifolia in Selected Cancer Cell Lines." 07/01/2013 - "In addition, compounds 3 and 5 showed significant cytotoxic activity against KB, LU-1, LNCaP, and HL-60 cancer cells with IC50 values around 1-4 μg/mL. Compounds 9-methoxycanthin-6-one (3) and niloticine (5) have been discovered for the first time from the Brucea genus." 01/18/2022 - "The aims of these studies were to investigate the in vitro anti-cancer activities of 9-methoxycanthin-6-one against ovarian cancer (A2780, SKOV-3), breast cancer (MCF-7), colorectal cancer (HT29), skin cancer (A375) and cervical cancer (HeLa) cell lines by using a Sulphorhodamine B assay, and to evaluate the mechanisms of action of 9-methoxycanthin-6-one via the Hoechst 33342 assay and proteomics approach. "
2.	Breast Neoplasms (Breast Cancer) 10/01/2003 - "These compounds were screened for in vitro cytotoxic and antimalarial activities, and 9-methoxycanthin-6-one (4) and canthin-6-one (5) demonstrated significant cytotoxicity against human lung cancer (A-549) and human breast cancer (MCF-7) cell lines." 01/18/2022 - "The aims of these studies were to investigate the in vitro anti-cancer activities of 9-methoxycanthin-6-one against ovarian cancer (A2780, SKOV-3), breast cancer (MCF-7), colorectal cancer (HT29), skin cancer (A375) and cervical cancer (HeLa) cell lines by using a Sulphorhodamine B assay, and to evaluate the mechanisms of action of 9-methoxycanthin-6-one via the Hoechst 33342 assay and proteomics approach. "
3.	Colorectal Neoplasms (Colorectal Cancer) 01/18/2022 - "The aims of these studies were to investigate the in vitro anti-cancer activities of 9-methoxycanthin-6-one against ovarian cancer (A2780, SKOV-3), breast cancer (MCF-7), colorectal cancer (HT29), skin cancer (A375) and cervical cancer (HeLa) cell lines by using a Sulphorhodamine B assay, and to evaluate the mechanisms of action of 9-methoxycanthin-6-one via the Hoechst 33342 assay and proteomics approach. "
4.	Skin Neoplasms (Skin Cancer) 01/18/2022 - "The aims of these studies were to investigate the in vitro anti-cancer activities of 9-methoxycanthin-6-one against ovarian cancer (A2780, SKOV-3), breast cancer (MCF-7), colorectal cancer (HT29), skin cancer (A375) and cervical cancer (HeLa) cell lines by using a Sulphorhodamine B assay, and to evaluate the mechanisms of action of 9-methoxycanthin-6-one via the Hoechst 33342 assay and proteomics approach. "
5.	Ovarian Neoplasms (Ovarian Cancer) 01/18/2022 - "The aims of these studies were to investigate the in vitro anti-cancer activities of 9-methoxycanthin-6-one against ovarian cancer (A2780, SKOV-3), breast cancer (MCF-7), colorectal cancer (HT29), skin cancer (A375) and cervical cancer (HeLa) cell lines by using a Sulphorhodamine B assay, and to evaluate the mechanisms of action of 9-methoxycanthin-6-one via the Hoechst 33342 assay and proteomics approach. "

Related Drugs and Biologics

1.	lissamine rhodamine B (sulforhodamine B)
2.	bisbenzimide ethoxide trihydrochloride (Hoechst 33342)
3.	Antimalarials (Antimalarial Agents)
4.	canthin-6-one