3beta(N- (N',N',N'- triethylaminopropane)carbamoyl)cholesterol iodide

cholesterol-based cationic liposome

Also Known As:

TEAPC-Chol

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Cholestanes
      - Sterols: 2245
        Cholesterol: 67133
        3beta(N-(N',N',N'-triethylaminopropane)carbamoyl)cholesterol iodide: 4
      - Cholestenes
        Cholesterol: 67133
        3beta(N-(N',N',N'-triethylaminopropane)carbamoyl)cholesterol iodide: 4
Lipids: 114793
- Membrane Lipids: 1591
  - Sterols: 2245
    - Cholesterol: 67133
      - 3beta(N-(N',N',N'-triethylaminopropane)carbamoyl)cholesterol iodide: 4

Experts

1.	Briane, D: 3 articles (04/2003 - 08/2002)
2.	Cao, A: 3 articles (04/2003 - 08/2002)
3.	Taillandier, E: 3 articles (04/2003 - 08/2002)
4.	Naejus, R: 2 articles (04/2003 - 11/2002)
5.	Reynier, P: 2 articles (04/2003 - 11/2002)
6.	Lievre, N: 2 articles (11/2002 - 08/2002)
7.	Breau, J L: 1 article (04/2003)
8.	Jaurand, M C: 1 article (04/2003)
9.	Kraemer, M: 1 article (04/2003)
10.	Oudar, O: 1 article (04/2003)

Related Diseases

1.	Neoplasms (Cancer) 07/01/2002 - "We investigated by transmission electron microscopy the cellular route in tumor MCF7 cells of DNA labeled with digoxigenin, carried by cationic liposomes (Lip+) prepared from TMAEC-Chol [3 beta(N-(N',N',N'-trimethylaminoethane)-carbamoyl)cholesterol iodide] and TEAPC-Chol [3 beta(N-(N',N',N'-triethylaminopropane)-carbamoyl)cholesterol iodide], two cholesterol-based cationic lipids containing a quaternary ammonium. "
2.	Mesothelioma 04/01/2003 - "Results showed that an efficient transfer of plasmids containing the reporter gene pCMV-beta galactosidase vectorized by TMAEC-Chol/DOPE and TEAPC-Chol/DOPE liposomes into mesothelioma FR cells was obtained as assessed by luminometric measurements of beta-galactosidase activity. "
3.	Melanoma (Melanoma, Malignant) 11/01/2002 - "In vitro and in vivo transgene expression in B16-F10 melanoma cells has been investigated using an original cationic liposome prepared with triethyl aminopropane carbamoyl cholesterol iodide (TEAPC-Chol) as carrier. "
4.	Brain Neoplasms (Brain Tumor) 08/31/2002 - "These results would be useful for gaining knowledge about the potential for the cationic liposome TEAPC-Chol/DOPE to transfect brain tumors efficiently."
5.	Malignant Mesothelioma 04/01/2003 - "In this work, the tumor suppressor gene p16 was efficiently transferred into FR cells isolated from a patient with malignant mesothelioma using cationic liposomes prepared from trimethyl aminoethane carbamoyl cholesterol (TMAEC-Chol) and triethyl aminopropane carbamoyl cholesterol (TEAPC-Chol). "

Related Drugs and Biologics

1.	Liposomes (Liposome)
2.	Cholesterol
3.	Iodides
4.	3beta(N- (N',N',N'- trimethylaminoethane)carbamoyl)cholesterol iodide
5.	Ammonium Compounds
6.	Lipids
7.	DNA (Deoxyribonucleic Acid)
8.	Digoxigenin
9.	beta-Galactosidase (Lactaid)