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corylin

from Psoralea corylifolia (Leguminosae), has osteoblastic proliferation stimulating activity; structure in first source

Networked: 19 relevant articles (4 outcomes, 9 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        corylin: 19
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        corylin: 19

Experts

1.	Leu, Yann-Lii: 4 articles (02/2022 - 01/2018)
2.	Chen, Chin-Chuan: 4 articles (01/2021 - 01/2018)
3.	Li, Chia-Yang: 3 articles (10/2021 - 11/2017)
4.	Liu, Po-Len: 3 articles (10/2021 - 11/2017)
5.	Wang, Shu-Chi: 3 articles (10/2021 - 11/2017)
6.	Wang, Shu-Huei: 3 articles (01/2021 - 01/2018)
7.	Liu, Shourong: 2 articles (12/2021 - 11/2021)
8.	Dong, Tina Ting-Xia: 2 articles (03/2021 - 01/2020)
9.	Kwan, Kenneth Kin-Leung: 2 articles (03/2021 - 01/2020)
10.	Tsim, Karl Wah-Keung: 2 articles (03/2021 - 01/2020)

Related Diseases

1.	Body Weight (Weight, Body) 02/28/2022 - "The results showed corylin could improved the survival rate and colon length, maintained body weight, and ameliorated the inflammatory response in the colon. " 01/01/2021 - "Moreover, corylin also strikingly reduced body weight and fat accumulation and increased insulin sensitivity, mitochondrial biogenesis, and β-oxidation in HFD- and DIO-treated mice. "
2.	Acute Lung Injury 10/14/2021 - "Corylin Ameliorates LPS-Induced Acute Lung Injury via Suppressing the MAPKs and IL-6/STAT3 Signaling Pathways."
3.	Wounds and Injuries (Trauma) 01/01/2023 - "Corylin accelerated wound healing through SIRT1 and PI3K/AKT signaling: a candidate remedy for chronic non-healing wounds." 01/01/2023 - "Furthermore, inhibition of PI3K/AKT and sirtuin 1 pathway with LY294002 and EX527 prevent the therapeutic potency of corylin against chronic wounds. " 01/01/2023 - "Results: We showed that corylin, a main flavonoid extracted from Psoralea corylifolia L, reduced inflammatory responses, promoted collagen deposition, and accelerated the healing of full-thickness skin wounds in mice. "
4.	Ulcerative Colitis 02/01/2023 - "Corylin ameliorates chronic ulcerative colitis via regulating the gut-brain axis and promoting 5-hydroxytryptophan production in the colon."
5.	Hepatocellular Carcinoma (Hepatoma) 01/27/2018 - "In this study, we used cells and animal models to examine the antitumor effects of corylin on hepatocellular carcinoma (HCC) and then studied its downstream regulatory mechanisms. " 01/01/2018 - "In this study, we used cell functional assays to analyze the antitumor activity of corylin in hepatocellular carcinoma (HCC). " 01/27/2018 - "Corylin Suppresses Hepatocellular Carcinoma Progression via the Inhibition of Epithelial-Mesenchymal Transition, Mediated by Long Noncoding RNA GAS5." 01/01/2018 - "Corylin increases the sensitivity of hepatocellular carcinoma cells to chemotherapy through long noncoding RNA RAD51-AS1-mediated inhibition of DNA repair." 01/01/2023 - "The biological importance of corylin in hyperlipidemia, insulin resistance, atherosclerosis, hepatocellular carcinoma, and neurodisorders have also been presented in this work. "

Related Drugs and Biologics

1.	Sirtuin 1
2.	5-Hydroxytryptophan (5 Hydroxytryptophan)
3.	Flavonoids
4.	Serotonin (5 Hydroxytryptamine)
5.	Dextrans (Dextran)
6.	Antioxidants
7.	sodium sulfate (sodium bisulfate)
8.	Long Noncoding RNA
9.	Inflammasomes
10.	Therapeutic Uses

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Oral Administration