Hep-HSA

substitution of human serum albumin with negatively charged heparin

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Inflammation (Inflammations) 01/01/2020 - "Here an inflammation-targeting (IT) approach based on heparin-coated human serum albumin nanoparticles (HEP-HSA NPs) that utilize the increased intestinal permeability and changes in electrostatic interaction at the site of intestinal inflammation is described. "
2.	Colitis 01/01/2020 - "Using small-molecule and biologic drugs as a model for drug combination, the HEP-HSA NPs demonstrate the capacity to load both drugs simultaneously; the dual-drug loaded HEP-HSA NPs exhibit a higher anti-inflammatory effect than both of the single-drug loaded NPs in vitro and selectively bind to inflamed intestine after enema administration in vivo in a murine model of colitis. "

1.	Enema (Enemas)