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atractylenolide II

from Atractylodes ovata; structure in first source

Networked: 16 relevant articles (2 outcomes, 5 trials/studies)

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Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Sesquiterpenes: 1370
      - atractylenolide II: 16
- Lactones: 1549
  - atractylenolide II: 16

Experts

1.	Adlat, Salah: 2 articles (07/2021 - 12/2018)
2.	Jiang, Nan: 2 articles (07/2021 - 12/2018)
3.	Jiang, Xuehua: 2 articles (12/2017 - 09/2017)
4.	Wang, Ling: 2 articles (12/2017 - 09/2017)
5.	Wang, Ting: 2 articles (12/2017 - 09/2017)
6.	Yang, Yujie: 2 articles (12/2017 - 09/2017)
7.	Chou, Gui-Xin: 2 articles (11/2014 - 06/2011)
8.	Yu, Zhi-Ling: 2 articles (11/2014 - 06/2011)
9.	Cui, Xiao-Bing: 2 articles (06/2013 - 10/2006)
10.	Li, Wei: 2 articles (06/2013 - 10/2006)

Related Diseases

1.	Hypertension (High Blood Pressure) 07/13/2023 - "The study aimed to explore the effect of Atractylenolide II (ATL-II) on MF and oxidative stress in spontaneous hypertension rats (SHR). " 07/13/2023 - "Atractylenolide II ameliorates myocardial fibrosis and oxidative stress in spontaneous hypertension rats."
2.	Colorectal Neoplasms (Colorectal Cancer) 01/01/2019 - "In conclusion, the XIST/miR-30a-5p/ROR1 axis could be deemed as pivotal markers underlying colorectal cancer, and administration of atractylenolide II might improve the chemotherapeutic efficacy for colorectal cancer." 01/01/2019 - "Finally, atractylenolide II was discovered to slow down the viability and proliferation of colorectal cancer cells (P < 0.05). " 01/01/2019 - "This investigation was conducted to elucidate whether atractylenolide II could reverse the role of lncRNA XIST/miR-30a-5p/ROR1 axis in modulating chemosensitivity of colorectal cancer cells. " 01/01/2019 - "Atractylenolide II reverses the influence of lncRNA XIST/miR-30a-5p/ROR1 axis on chemo-resistance of colorectal cancer cells."
3.	Fibrosis (Cirrhosis) 07/13/2023 - "Atractylenolide II ameliorates myocardial fibrosis and oxidative stress in spontaneous hypertension rats."
4.	Breast Neoplasms (Breast Cancer) 07/01/2021 - "In this research, atractylenolide II (ATR II) on apoptosis, cell cycle cells via ER pathway in breast cancer (MDA-MB-231 and MCF-7) cells are assessed. " 07/01/2021 - "Atractylenolide II induces cell cycle arrest and apoptosis in breast cancer cells through ER pathway." 09/29/2017 - "Collectively, our results suggested that atractylenolide II could protect against mammary tumorigenesis both in vivo and in vitro via activating Nrf2-ARE signaling pathway, which supported atractylenolide II as a novel chemopreventive agent of breast cancer." 12/01/2017 - "Our study firstly found MXP active components including quercetin, kaempferol, and atractylenolide II. Our results firstly demonstrate that NRF2-NQO1 pathway plays an essential role in mediating the activity of MXP and its active components in breast cancer chemoprevention. "
5.	Experimental Melanoma 11/01/2014 - "Our previous studies showed that atractylenolide II (AT-II) has antimelanoma effects in B16 melanoma cells. " 06/14/2011 - "Atractylenolide II induces G1 cell-cycle arrest and apoptosis in B16 melanoma cells."

Related Drugs and Biologics

1.	Quercetin
2.	kaempferol
3.	atractylenolide I
4.	atractylenolide III
5.	Sesquiterpenes
6.	Lactones
7.	Baizhu
8.	Phytochemicals
9.	Long Noncoding RNA
10.	Transcription Factor RelA

Related Therapies and Procedures

1.	Chemoprevention