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alisol A 24-acetate

isolated from Alismatis Rhizoma; structure in first source

Also Known As:

24-acetylalisol A

Networked: 13 relevant articles (4 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Cholestanes
      - Cholestenes
        Cholestenones
        alisol A 24-acetate: 13

Experts

1.	Wei, Wei: 4 articles (02/2022 - 05/2018)
2.	Lu, Taotao: 3 articles (02/2022 - 01/2021)
3.	Xue, Xiehua: 3 articles (02/2022 - 01/2021)
4.	Zhou, Yangjie: 2 articles (02/2022 - 12/2021)
5.	Lu, Lu: 2 articles (12/2021 - 01/2021)
6.	Shen, Julian: 2 articles (12/2021 - 01/2021)
7.	Wang, Hong: 2 articles (12/2021 - 01/2021)
8.	Nam, Sang-Jip: 2 articles (01/2016 - 01/2015)
9.	Son, Young-Jin: 2 articles (01/2016 - 01/2015)
10.	Yee, Sung-Tae: 2 articles (01/2016 - 01/2015)

Related Diseases

1.	Non-alcoholic Fatty Liver Disease 08/01/2018 - "Alisol A 24-acetate ameliorates nonalcoholic steatohepatitis by inhibiting oxidative stress and stimulating autophagy through the AMPK/mTOR pathway." 01/01/2016 - "Thereby, Alisol A 24-acetate could be a promising candidate for the treatment of NAFLD." 01/01/2016 - "The present study was conducted to investigate the therapeutic effects and potential mechanisms of Alisol A 24-acetate against hepatic steatosis in a free fatty acids (FFAs) induced NAFLD cell model. " 01/01/2019 - "orientale and its chemical constituents including Alisol A 24-acetate, Alisol B 23-acetate, Alisol F, and Alismol against NAFLD and metabolic syndrome. "
2.	Inflammation (Inflammations) 12/01/2021 - "However, alisol A 24-acetate treatment suppressed inflammation, improved migration and invasion abilities, increased Bcl-2 expression, inhibited Bax expression, and repressed apoptosis and miR92a-3p overexpression in OGD-induced BMECs. " 02/07/2022 - "Alisol A 24-acetate (24A) exerts a strong inhibitory effect on inflammation and cell apoptosis. " 01/01/2016 - "These results demonstrated that Alisol A 24-acetate effectively ameliorated hepatic steatosis likely through Adiponectin, which activated AMPKα signaling pathways via down-regulating SREBP-1c, ACC, FAS and up-regulating CPT1 and ACOX1, and inhibited inflammation. "
3.	Postmenopausal Osteoporosis 01/09/2016 - "These results suggest alisol A 24-acetate effectively prevents bone loss in OVX mice, and that it can be considered a potential therapeutic for the treatment of postmenopausal osteoporosis. "
4.	Osteoarthritis 01/01/2023 - "Alisol A 24-acetate ameliorates osteoarthritis progression by inhibiting reactive oxygen species and inflammatory response through the AMPK/mTOR pathway."
5.	Cerebrovascular Disorders (Cerebrovascular Occlusion) 12/01/2021 - "These findings suggest that alisol A 24-acetate exerts antiapoptotic effects on OGD-induced BMECs through miR-92a-3p inhibition by targeting the Bcl-2 gene, indicating its potential for BMECs protection and as a novel therapeutic agent for the treatment of cerebrovascular disease."

Related Drugs and Biologics

1.	Reactive Oxygen Species (Oxygen Radicals)
2.	Triterpenes
3.	Therapeutic Uses
4.	Nonesterified Fatty Acids (NEFA)
5.	oxidized low density lipoprotein
6.	alisol B 23-acetate
7.	alisol A
8.	Adiponectin
9.	Sterol Regulatory Element Binding Protein 1
10.	Neuroprotective Agents