wentilactone B

previously reported structure incorrect; hydroxy group found to be in 2alpha-position instead

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

1.	Neoplasm Metastasis (Metastasis) 06/06/2013 - "Wentilactone B (WB), a tetranorditerpenoid derivative extracted from the marine algae-derived endophytic fungus Aspergillus wentii EN-48, has been shown to trigger apoptosis and inhibit metastasis in HCC cell lines. " 01/01/2012 - "In conclusion, Wentilactone B inhibited the growth of SMMC-7721 cells by triggering apoptosis and inhibiting metastasis." 01/01/2012 - "In addition, Wentilactone B could inhibit the metastasis of SMMC-7721 cells, which was detected by colony formation, scratch migration and a transwell assay, and could induce a series of intracellular events, including the down-regulation of CD44 and epidermal growth factor receptor proteins. "
2.	Hepatocellular Carcinoma (Hepatoma) 06/06/2013 - "Wentilactone B induces G2/M phase arrest and apoptosis via the Ras/Raf/MAPK signaling pathway in human hepatoma SMMC-7721 cells." 01/01/2012 - "Wentilactone B from Aspergillus wentii induces apoptosis and inhibits proliferation and migration of human hepatoma SMMC-7721 cells."