N- (N- ((1- tert- butyloxycarbonyl)indolin- 2- carbonyl)indolin- 2- carbonyl)- (N- epsilon- benzyloxycarbonyl)- 2- lysine methyl ester

binds cyclosporine receptor; structure in first source

Also Known As:

D 43787; D-43787; D43787

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Eosinophilia 05/01/2002 - "In vivo, D-43787 potently inhibited late-phase eosinophilia in actively sensitized and challenged guinea pigs (10 mg/kg, i.p.: 51%) and Brown-Norway rats (1 mg/kg, intrapulmonary: 66% 30 mg/kg, i.p.: 50%). "
2.	Edema (Dropsy) 05/01/2002 - "In adjuvant-induced arthritis, D-43787 (10-40 mg/kg, b.i.d., i.p.) dose dependently reduced edema development on both hind paws. "
3.	Arthritis (Polyarthritis) 05/01/2002 - "In adjuvant-induced arthritis, D-43787 (10-40 mg/kg, b.i.d., i.p.) dose dependently reduced edema development on both hind paws. "