HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

3-O-methylfunicone

derived from Penicillium pinophilum; structure in first source

Networked: 8 relevant articles (0 outcomes, 4 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Pyrones: 35
      - 3-O-methylfunicone: 8

Experts

1.	Nicoletti, Rosario: 3 articles (01/2022 - 11/2007)
2.	Buommino, E: 3 articles (10/2011 - 08/2009)
3.	De Filippis, A: 3 articles (10/2011 - 08/2009)
4.	Nicoletti, R: 3 articles (10/2011 - 08/2009)
5.	Tufano, M A: 3 articles (10/2011 - 08/2009)
6.	Buommino, Elisabetta: 2 articles (08/2012 - 11/2007)
7.	Ciavatta, Maria Letizia: 2 articles (08/2012 - 11/2007)
8.	De Filippis, Anna: 2 articles (08/2012 - 11/2007)
9.	Tufano, Maria Antonietta: 2 articles (08/2012 - 11/2007)
10.	Ciavatta, M L: 2 articles (10/2011 - 04/2010)

Related Diseases

1.	Infections 01/15/2022 - "Antiviral Property of the Fungal Metabolite 3-O-Methylfunicone in Bovine Herpesvirus 1 Infection." 11/11/2022 - "Previous examinations of benzo-γ-pyrone 3-O-methylfunicone (OMF), obtained from Talaromyces pinophilus, showed that it reduces the infectivity of hepatitis C virus and bovine herpesvirus 1. Based on this evidence, this study evaluated the antiviral ability of OMF against CCoV infection in a canine fibrosarcoma (A72) cell line. "
2.	Breast Neoplasms (Breast Cancer) 10/01/2011 - "In the study described here, anti-proliferative effects of 3-O-methylfunicone (OMF), a metabolite from Penicillium pinophilum, were investigated on human breast cancer MCF-7 cells and cancer stem cells selected as mammospheres derived from MCF-7s. " 10/01/2011 - "3-O-methylfunicone, from Penicillium pinophilum, is a selective inhibitor of breast cancer stem cells." 11/01/2007 - "Here, we demonstrate that 3-O-methylfunicone (OMF), a secondary metabolite produced by Penicillium pinophilum, affects cell proliferation and motility of breast cancer MCF-7 cells, downregulating alphavbeta5 integrin, and inhibiting MMP-9 secretion. " 11/01/2007 - "3-O-methylfunicone produced by penicillium pinophilum affects cell motility of breast cancer cells, downregulating alphavbeta5 integrin and inhibiting metalloproteinase-9 secretion."
3.	Neoplasm Metastasis (Metastasis) 08/01/2009 - "The aim of this study was to demonstrate whether 3-O-methylfunicone (OMF), a metabolite of Penicillium pinophilum, has the ability to arrest cell population growth and to induce apoptosis in A375P (parental) and A375M (metastasis derivatived) melanoma cell lines. "
4.	Melanoma (Melanoma, Malignant) 08/01/2009 - "3-O-methylfunicone, a metabolite of Penicillium pinophilum, inhibits proliferation of human melanoma cells by causing G(2) + M arrest and inducing apoptosis." 08/01/2009 - "The aim of this study was to demonstrate whether 3-O-methylfunicone (OMF), a metabolite of Penicillium pinophilum, has the ability to arrest cell population growth and to induce apoptosis in A375P (parental) and A375M (metastasis derivatived) melanoma cell lines. "
5.	Fibrosarcoma 11/11/2022 - "Effectiveness of the Fungal Metabolite 3-O-Methylfunicone towards Canine Coronavirus in a Canine Fibrosarcoma Cell Line (A72)." 11/11/2022 - "Previous examinations of benzo-γ-pyrone 3-O-methylfunicone (OMF), obtained from Talaromyces pinophilus, showed that it reduces the infectivity of hepatitis C virus and bovine herpesvirus 1. Based on this evidence, this study evaluated the antiviral ability of OMF against CCoV infection in a canine fibrosarcoma (A72) cell line. "

Related Drugs and Biologics

1.	Antiviral Agents (Antivirals)
2.	funicone
3.	Cisplatin (Platino)
4.	integrin alphaVbeta5