HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

3,5-dipentadecyloxybenzamidine hydrochloride

structure in first source

Also Known As:

TRX-20

Networked: 3 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amidines: 14
  - Benzamidines: 5
    - 3,5-dipentadecyloxybenzamidine hydrochloride: 3
Lipids: 114793
- Fatty Acids: 27405
  - 3,5-dipentadecyloxybenzamidine hydrochloride: 3

Experts

1.	Kimura, Junji: 3 articles (05/2007 - 08/2002)
2.	Kondo, Masayo: 2 articles (05/2007 - 08/2002)
3.	Kawahara, Kazuo: 1 article (05/2007)
4.	Miyajima, Masaharu: 1 article (05/2007)
5.	Morimoto, Katsumi: 1 article (05/2007)
6.	Tomino, Yasuhiko: 1 article (05/2007)
7.	Ushijima, Hideto: 1 article (05/2007)
8.	Hagiwara, Hitomi: 1 article (01/2007)
9.	Harigai, Takashi: 1 article (01/2007)
10.	Ishizuka, Takanobu: 1 article (01/2007)

Related Diseases

1.	Neoplasms (Cancer) 08/01/2002 - "In vitro, TRX-20 liposomes, but not plain PEG liposomes, avidly bound to and were readily internalized by highly metastatic tumor cells such as LM8G5 and ACHN cells, which express large amounts of CS on the cell surface. " 08/01/2002 - "LM8G5 tumor revealed that cisplatin-loaded TRX-20 liposomes were significantly more effective in reducing the local tumor growth than cisplatin-loaded plain PEG liposomes or free cisplatin. " 08/01/2002 - "Furthermore, the cisplatin-loaded TRX-20 liposomes markedly suppressed metastatic spreading of LM8G5 tumor cells to the liver, significantly increasing the survival time of the tumor-bearing mice. " 08/01/2002 - "When TRX-20 liposomes were loaded with cisplatin, they effectively killed the CS-expressing tumor cells in vitro, whereas cisplatin-PEG liposomes lacking TRX-20 were totally ineffective. "
2.	Glomerulonephritis 05/01/2007 - "In this study, we investigated targeting the delivery of PEG-modified liposomes containing TRX-20 (TRX-liposomes) to mesangial cells and evaluated their pharmacokinetic behavior in a rat experimental glomerulonephritis model, using prednisolone phosphate (PSLP) as a model drug. "
3.	Rheumatoid Arthritis 01/01/2007 - "To evaluate the potential of using prednisolone phosphate (PSLP)-containing 3,5-dipentadecyloxybenzamidine hydrochloride (TRX-20) liposomes to treat rheumatoid arthritis (RA), we examined their ability to bind human fibroblast-like synovial (HFLS) cells and their effects in these cells. " 01/01/2007 - "Prednisolone phosphate-containing TRX-20 liposomes inhibit cytokine and chemokine production in human fibroblast-like synovial cells: a novel approach to rheumatoid arthritis therapy."

Related Drugs and Biologics

1.	Liposomes (Liposome)
2.	Cisplatin (Platino)
3.	prednisolone phosphate
4.	Chemokines
5.	Cytokines

Related Therapies and Procedures

1.	Therapeutics