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carboxyethylphosphoramide mustard

a 4-hydroxycyclophosphamide metabolite

Also Known As:

CEPM cpd

Networked: 4 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Halogenated Hydrocarbons: 42
    - Mustard Compounds: 3
      - Nitrogen Mustard Compounds: 2
        Phosphoramide Mustards: 5
        carboxyethylphosphoramide mustard: 4
- Organophosphorus Compounds: 300
  - Phosphoramides: 8
    - Phosphoramide Mustards: 5
      - carboxyethylphosphoramide mustard: 4

Experts

1.	Campagne, Olivia: 2 articles (01/2020 - 01/2019)
2.	Nair, Sreenath: 2 articles (01/2020 - 01/2019)
3.	Zhong, Bo: 2 articles (01/2020 - 01/2019)
4.	Gajjar, Amar: 1 article (01/2020)
5.	Huang, Jie: 1 article (01/2020)
6.	Lin, Tong: 1 article (01/2020)
7.	Onar-Thomas, Arzu: 1 article (01/2020)
8.	Robinson, Giles: 1 article (01/2020)
9.	Stewart, Clinton F: 1 article (01/2020)
10.	Davis, Abigail: 1 article (01/2019)

Related Diseases

1.	Cardiotoxicity 08/14/2017 - "In previous studies, we suggested that for CY-induced cardiotoxicity, whereas acrolein is the key toxic metabolite, carboxyethylphosphoramide mustard (CEPM) is protective. "
2.	Multiple Sclerosis 01/01/2017 - "The aim of this study was to evaluate the enantioselective pharmacokinetics of cyclophosphamide and its metabolites 4-hydroxycyclophosphamide and carboxyethylphosphoramide mustard in patients with systemic or multiple sclerosis. "
3.	Neoplasms (Cancer) 01/01/2019 - "We performed cerebral microdialysis to characterize the brain penetration of cyclophosphamide (130 mg/kg, IP) and its metabolites [4-hydroxy-cyclophosphamide (4OH-CTX) and carboxyethylphosphoramide mustard (CEPM)] in non-tumor bearing mice and mice bearing orthotopic Group 3 medulloblastoma. "
4.	Medulloblastoma 01/01/2019 - "We performed cerebral microdialysis to characterize the brain penetration of cyclophosphamide (130 mg/kg, IP) and its metabolites [4-hydroxy-cyclophosphamide (4OH-CTX) and carboxyethylphosphoramide mustard (CEPM)] in non-tumor bearing mice and mice bearing orthotopic Group 3 medulloblastoma. "
5.	Brain Neoplasms (Brain Tumor) 01/01/2020 - "To characterize the population pharmacokinetics of cyclophosphamide, active 4-hydroxy-cyclophosphamide (4OH-CTX), and inactive carboxyethylphosphoramide mustard (CEPM), and their associations with hematologic toxicities in infants and young children with brain tumors. "

Related Drugs and Biologics

1.	Cyclophosphamide (Cytoxan)
2.	Acrolein (Aqualin)
3.	4-hydroxycyclophosphamide