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N- (alpha- ethylbenzyl)- 3- (carboxymethoxy)- 2- phenylquinoline- 4- carboxamide

SB-235375 is the ((-)-(S))-isomer; structure in first source

Also Known As:

SB 235375; SB-235375; SB235375

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Acetates: 4994
      - N-(alpha-ethylbenzyl)-3-(carboxymethoxy)-2-phenylquinoline-4-carboxamide: 1
Lipids: 114793
- Fatty Acids: 27405
  - Volatile Fatty Acids: 3052
    - Acetates: 4994
      - N-(alpha-ethylbenzyl)-3-(carboxymethoxy)-2-phenylquinoline-4-carboxamide: 1
Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinolines: 146
      - N-(alpha-ethylbenzyl)-3-(carboxymethoxy)-2-phenylquinoline-4-carboxamide: 1

Experts

1.	Barone, Frank C: 1 article (01/2002)
2.	Bush, Brian: 1 article (01/2002)
3.	Foley, James J: 1 article (01/2002)
4.	Giardina, Giuseppe A M: 1 article (01/2002)
5.	Griswold, Don E: 1 article (01/2002)
6.	Grugni, Mario: 1 article (01/2002)
7.	Hay, Douglas W P: 1 article (01/2002)
8.	Kilian, David: 1 article (01/2002)
9.	Kotzer, Charles J: 1 article (01/2002)
10.	Legos, Jeffrey J: 1 article (01/2002)

Related Diseases

1.	Miosis 01/01/2002 - "Intravenous SB 235375 produced a dose-related inhibition of miosis induced by i.v. senktide in the rabbit (ED(50) of 0.56 mg/kg). "
2.	Cough 01/01/2002 - "Intraperitoneal SB 235375 (10-30 mg/kg) inhibited citric acid-induced cough and airways hyper-reactivity in guinea pigs. " 01/01/2002 - "III. SB 235375, a low central nervous system-penetrant, potent and selective neurokinin-3 receptor antagonist, inhibits citric acid-induced cough and airways hyper-reactivity in guinea pigs."

Related Drugs and Biologics

1.	Citric Acid (Citrate)
2.	Neurokinin-3 Receptors
3.	senktide