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(3,5,5,8,8,- pentamethyl- 5,6,7,8- tetrahydronaphthalen- 2- yl) (5 carboxypyrid-2-yl)sulfide

a retinoid X receptor agonist

Also Known As:

AGN 192849

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Lipids: 114793
- Fatty Acids: 27405
  - Unsaturated Fatty Acids: 8236
    - (3,5,5,8,8,-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl) (5 carboxypyrid-2-yl)sulfide: 1
Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthalenes: 18
        Tetrahydronaphthalenes: 1
        (3,5,5,8,8,-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl) (5 carboxypyrid-2-yl)sulfide: 1
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthalenes: 18
    - Tetrahydronaphthalenes: 1
      - (3,5,5,8,8,-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl) (5 carboxypyrid-2-yl)sulfide: 1

Experts

1.	Beard, R L: 1 article (12/2001)
2.	Chandraratna, R A: 1 article (12/2001)
3.	Escobar, M: 1 article (12/2001)
4.	Standeven, A M: 1 article (12/2001)
5.	Thacher, S M: 1 article (12/2001)
6.	Vuligonda, V: 1 article (12/2001)
7.	Yuan, Y D: 1 article (12/2001)

Related Diseases

1.

Hypertriglyceridemia

12/01/2001 - "We have now demonstrated that hypertriglyceridemia induced by an RAR agonist, AGN 190121 [4-[4-(2',6',6'-trimethylcyclohex-1-enyl)-but-1-yne-3-enyl]benzoic acid], is substantially potentiated by the RXR-selective agonists AGN 191701 [(E) 2-[2-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)propen-1-yl]-4-thiophene-carboxylic acid] and AGN 192849 [(3,5,5,8,8,-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl) (5 carboxypyrid-2-yl)sulfide] in a dose-dependent manner. "

Related Drugs and Biologics

1.	Benzoic Acid (Potassium Benzoate)
2.	Thiophenes
3.	Sulfides (Thioethers)
4.	Carboxylic Acids
5.	AGN 191701
6.	AGN 190121